胺类清洁剂/消毒剂产品Korsolex AF的杀分枝杆菌及杀结核菌活性

Mycobactericidal and tuberculocidal activity of Korsolex AF, an amine detergent/disinfectant product.

作者信息

Hernández A, Martró E, Matas L, Jiménez A, Ausina V

机构信息

Servicio de Microbiología, Hospital Universitario Germans Trias i Pujol, Departamento de Genética y Microbiología, Facultad de Medicina, Universidad Autónoma de Barcelona, 08916 Badalona, Barcelona, Spain.

出版信息

J Hosp Infect. 2005 Jan;59(1):62-6. doi: 10.1016/j.jhin.2004.05.021.

DOI:10.1016/j.jhin.2004.05.021

PMID:15571855

Abstract

The mycobactericidal and tuberculocidal activities of Korsolex AF against Mycobacterium tuberculosis, Mycobacterium avium-Mycobacterium intracellulare (MAI), Mycobacterium kansasii and Mycobacterium chelonae were determined using quantitative suspension and carrier tests. The effects of organic load and hard water were also considered. A clinical isolate of MAI was the most resistant of the four test organisms. A 2% solution had good mycobactericidal and tuberculocidal activities after 30 min of exposure. Although further evaluation using European standard tests is necessary, we conclude that Korsolex AF appears to be a promising product for the disinfection of hospital instruments contaminated with mycobacteria.

摘要

使用定量悬浮和载体试验测定了Korsolex AF对结核分枝杆菌、鸟分枝杆菌-胞内分枝杆菌（MAI）、堪萨斯分枝杆菌和龟分枝杆菌的杀分枝杆菌和杀结核菌活性。还考虑了有机负荷和硬水的影响。MAI的一株临床分离株是四种受试微生物中耐药性最强的。2%的溶液在暴露30分钟后具有良好的杀分枝杆菌和杀结核菌活性。尽管有必要使用欧洲标准试验进行进一步评估，但我们得出结论，Korsolex AF似乎是一种用于消毒被分枝杆菌污染的医院器械的有前景的产品。