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The efficacy of the disinfection of bronchoscopes contaminated in vitro with Mycobacterium tuberculosis and Mycobacterium avium-intracellulare in sputum: a comparison of Sactimed-I-Sinald and glutaraldehyde.

作者信息

Nicholson G, Hudson R A, Chadwick M V, Gaya H

机构信息

Department of Microbiology, Royal Brompton Hospital, London, UK.

出版信息

J Hosp Infect. 1995 Apr;29(4):257-64. doi: 10.1016/0195-6701(95)90272-4.

DOI:10.1016/0195-6701(95)90272-4
PMID:7658005
Abstract

The efficacy of Sactimed-I-Sinald and glutaraldehyde was tested against clinical isolates of Mycobacterium tuberculosis (MTB) and Mycobacterium avium-intracellulare (MAI). An in-use method demonstrated that over 10 disinfection cycles, using an auto-disinfector and a contact time of 60 min, MTB was eradicated in 10 out of 10 cycles with Sactimed-I-Sinald and five out of 10 cycles for glutaraldehyde. For MAI, Sactimed-I-Sinald showed a 5 log reduction at a 60 min contact time, which was not seen with glutaraldehyde. Although further evaluation is necessary, Sactimed-I-Sinald appears a promising alternative to glutaraldehyde.

摘要

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