Sadat-Ali Mir, Al-Habdan Ibrahim M, Al-Mulhim Fatma A, El-Hassan Abdallah Y
Department of Orthopedic Surgery, King Khalid University Hospital, PO Box 40071, Al-Khobar 31952, Kingdom of Saudi Arabia.
Saudi Med J. 2004 Nov;25(11):1623-5.
Osteoporosis is reported to be common among postmenopausal Saudi women. The reported incidence varies between 50-60%. Different machines were used to reach these conclusions. At present it is believed that dual energy x-ray absorptiometry (DEXA) is the most accurate method to diagnose osteoporosis. This study was conducted to measure bone mineral density (BMD) measurement of lumbar spine and the upper femur of Saudi postmenopausal women attending orthopedic clinic with unrelated complaints.
This study comprises of 256 patients attending orthopedic clinics at the King Fahd Hospital of the University, Al-Khobar, Kingdom of Saudi Arabia between January 2002 and June 2003. The data gathered was age, duration of menopause, height and weight for body mass index (BMI) calculation. Women with secondary osteoporosis were excluded from the study. Patients' orthopedic complaints were also recorded in the database. Bone mineral density measurements were carried out using Hologic total body DEXA machine. The data were analyzed using SPSS package.
The data of 256 patients was available for analysis. The average age of patients screened was 57.62 years (49-76) SD +/- 6.71. The BMI was 21.3-42.9 Kg/m2 (SD +/- 5.34). The BMD of the lumbar spine was 0.785 gm/cm2 (0.527-1.023) SD +/-0.142 and that of the hip region was 0.764 gm/cm2 (0. 500-1.069) SD +/- 0.149. As per the WHO classification 59 women (23%) were classified as normal with T score of -0.82, 78 (30.5%) as osteopenic with T score -2.5 and 119 (46.7%) as osteoporosis with T score -3.58. When the BMD of the hip was analyzed 62 (24.2%) were normal T score -1.0, 81 (31.6%) as osteopenic, T score -2.5 and 113 (44.1%) as osteoporotic, with a T score of -3.1. On the basis of analysis of the lumbar spine 190 (74.2%) had increased risk of fracture as compared to the analysis of hip 59% were at increased risk of fracture.
Our results indicate that postmenopausal Saudi women suffer from osteoporosis and osteopenia higher than those from other parts of the country. Necessary steps are needed so as to avoid osteoporosis and its complications which could end up in epidemic proportions.
据报道，骨质疏松症在沙特绝经后女性中很常见。报道的发病率在50%至60%之间。为得出这些结论使用了不同的仪器。目前认为，双能X线吸收法（DEXA）是诊断骨质疏松症最准确的方法。本研究旨在测量在骨科门诊就诊、有无关主诉的沙特绝经后女性腰椎和股骨上端的骨密度（BMD）。
本研究纳入了2002年1月至2003年6月期间在沙特阿拉伯王国胡拜尔法赫德国王大学医院骨科门诊就诊的256例患者。收集的数据包括年龄、绝经持续时间、身高和体重，用于计算体重指数（BMI）。继发性骨质疏松症女性被排除在研究之外。患者的骨科主诉也记录在数据库中。使用Hologic全身DEXA仪器进行骨密度测量。数据使用SPSS软件包进行分析。
256例患者的数据可供分析。筛查患者的平均年龄为57.62岁（49 - 76岁），标准差±6.71。BMI为21.3 - 42.9 Kg/m²（标准差±5.34）。腰椎的骨密度为0.785 gm/cm²（0.527 - 1.023），标准差±0.142，髋部区域的骨密度为0.764 gm/cm²（0.500 - 1.069），标准差±0.149。根据世界卫生组织分类，59名女性（23%）T值为 - 0.82被分类为正常，78名（30.5%）T值为 - 2.5被分类为骨量减少，119名（46.7%）T值为 - 3.58被分类为骨质疏松症。当分析髋部骨密度时，62名（24.2%）T值为 - 1.0为正常，81名（31.6%）T值为 - 2.5为骨量减少，113名（44.1%）T值为 - 3.1为骨质疏松症。基于腰椎分析显示，与髋部分析相比，190名（74.2%）骨折风险增加，59%的髋部分析显示骨折风险增加。
我们的结果表明，沙特绝经后女性患骨质疏松症和骨量减少的情况高于该国其他地区。需要采取必要措施以避免骨质疏松症及其可能发展为流行程度的并发症。
Zotero 插件