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细胞培养和组织工程任务的灵活自动化。

Flexible automation of cell culture and tissue engineering tasks.

作者信息

Knoll Alois, Scherer Torsten, Poggendorf Iris, Lütkemeyer Dirk, Lehmann Jürgen

机构信息

Department of Informatics, Technische Universität München, Boltzmannstrasse 3, 85748 Garching, Germany.

出版信息

Biotechnol Prog. 2004 Nov-Dec;20(6):1825-35. doi: 10.1021/bp049759v.

DOI:10.1021/bp049759v
PMID:15575718
Abstract

Until now, the predominant use cases of industrial robots have been routine handling tasks in the automotive industry. In biotechnology and tissue engineering, in contrast, only very few tasks have been automated with robots. New developments in robot platform and robot sensor technology, however, make it possible to automate plants that largely depend on human interaction with the production process, e.g., for material and cell culture fluid handling, transportation, operation of equipment, and maintenance. In this paper we present a robot system that lends itself to automating routine tasks in biotechnology but also has the potential to automate other production facilities that are similar in process structure. After motivating the design goals, we describe the system and its operation, illustrate sample runs, and give an assessment of the advantages. We conclude this paper by giving an outlook on possible further developments.

摘要

到目前为止,工业机器人的主要应用案例一直是汽车行业中的常规搬运任务。相比之下,在生物技术和组织工程领域,只有极少数任务实现了机器人自动化。然而,机器人平台和机器人传感器技术的新发展使得在很大程度上依赖人类与生产过程交互的工厂实现自动化成为可能,例如用于材料和细胞培养液的处理、运输、设备操作及维护。在本文中,我们展示了一个机器人系统,它不仅适用于生物技术中常规任务的自动化,而且有潜力使其他在工艺结构上类似的生产设施实现自动化。在阐述了设计目标之后,我们描述了该系统及其操作,展示了示例运行情况,并对其优势进行了评估。我们通过展望可能的进一步发展来结束本文。

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Regen Ther. 2018 Sep 19;9:89-99. doi: 10.1016/j.reth.2018.08.004. eCollection 2018 Dec.
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