Shotipruk Artiwan, Kiatsongserm Jirapat, Pavasant Prasert, Goto Motonobu, Sasaki Mitsuru
Department of Chemical Engineering, Chulalongkorn University, Patumwan, Payathai, Bangkok 10330, Thailand.
Biotechnol Prog. 2004 Nov-Dec;20(6):1872-5. doi: 10.1021/bp049779x.
This study examines pressurized hot water extraction of anthraquinones from dried roots of Morinda citrifolia (Noni). The effects of various operating conditions such as water temperature (110, 170, and 220 degrees C), and water flow rate (2, 4, and 6 mL min(-1)) on extraction yield and extraction rate were determined. At 220 degrees C, the extraction yield was the highest and was approximately 43.6 mg g(-1). Subcritical water extraction at 4 mL min(-1) or higher was found to be able to recover all the antraquinones present in the roots within 3 h of extraction, even at 170 degrees C. Pressure had no significant effect on the results for the range of temperatures studied. The flow rate of 6 mL min(-1) resulted in the highest extraction rate, but the extraction efficiency, as measured by the amount of anthraquinones extracted per unit volume of water was lower than that of 4 mL min(-1). Anthraquinones solubility in pressurized hot water was determined. The results indicate a presence of a mass transfer limitation in the extraction process from solid matrix.
本研究考察了从巴戟天（诺丽）干燥根中加压热水提取蒽醌的方法。测定了水温（110、170和220℃）、水流速（2、4和6 mL min⁻¹）等不同操作条件对提取率和提取速率的影响。在220℃时，提取率最高，约为43.6 mg g⁻¹。发现即使在170℃，以4 mL min⁻¹或更高的流速进行亚临界水提取，也能够在3小时内回收根中存在的所有蒽醌。在所研究的温度范围内，压力对结果没有显著影响。6 mL min⁻¹的流速导致最高的提取速率，但以每单位体积水提取的蒽醌量衡量的提取效率低于4 mL min⁻¹的流速。测定了蒽醌在加压热水中的溶解度。结果表明在从固体基质的提取过程中存在传质限制。
