• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

加压热水萃取作为天然产物的绿色技术——相对于水蒸馏和固液萃取的关键技术

Pressurized Hot Water Extraction as Green Technology for Natural Products as Key Technology with Regard to Hydrodistillation and Solid-Liquid Extraction.

作者信息

Knierim Larissa, Uhl Alexander, Schmidt Axel, Flemming Marcel, Höß Theresa, Treutwein Jonas, Strube Jochen

机构信息

Institute for Separation and Process Technology, Clausthal University of Technology, D-38678 Clausthal-Zellerfeld, Germany.

SKH GmbH, Koenigbacher Strasse 17, D-94496 Ortenburg, Germany.

出版信息

ACS Omega. 2024 Jul 10;9(29):31998-32010. doi: 10.1021/acsomega.4c03771. eCollection 2024 Jul 23.

DOI:10.1021/acsomega.4c03771
PMID:39072122
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11270720/
Abstract

Hydrodistillation and solid-liquid extraction with organic solvents or supercritical CO are standard technologies for natural product manufacturing. Within this technology, portfolio pressurized hot water technology is ranked as a green, sustainable, resilient, kosher and halal manufacturing process. Essential for sustainability is energy integration for heating and cooling the auxiliary water as well as product concentration without evaporation but with the aid of low energy consuming ultra- and nanofiltration membrane technology. The incorporation of modern unit operations, such as pressurized hot water extraction, along with inline measurement devices for Process Analytical Technology approaches, showcases a shift in traditional extraction processes. Traditional equipment and processes still dominate the manufacturing of plant extracts, yet leveraging innovative chemical process engineering methods offers promising avenues for the economic and ecological advancement of botanicals. Techniques such as modeling and process intensification with green technology hold potential in this regard. Digitalization and Industry 4.0 methodologies, including machine learning and artificial intelligence, play pivotal roles in sustaining natural product extraction manufacturing and can profoundly impact the future of human health.

摘要

水蒸馏以及用有机溶剂或超临界二氧化碳进行固液萃取是天然产物制造的标准技术。在这项技术中，组合式加压热水技术被列为一种绿色、可持续、有弹性、符合犹太教规和伊斯兰教规的制造工艺。可持续性的关键在于对辅助水进行加热和冷却以及产品浓缩时的能量整合，无需蒸发，而是借助低能耗的超滤和纳滤膜技术。现代单元操作的纳入，如加压热水萃取，以及过程分析技术方法中的在线测量装置，展示了传统萃取过程的转变。传统设备和工艺在植物提取物制造中仍占主导地位，但利用创新的化学过程工程方法为植物提取物的经济和生态发展提供了有前景的途径。诸如绿色技术建模和过程强化等技术在这方面具有潜力。数字化和工业4.0方法，包括机器学习和人工智能，在维持天然产物提取制造方面发挥着关键作用，并会对人类健康的未来产生深远影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/1e0c7c222ed9/ao4c03771_0016.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/5f80371df099/ao4c03771_0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/38a0a99f416f/ao4c03771_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/05f08a7e67f9/ao4c03771_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/ff62f9bc7734/ao4c03771_0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/62ddf99bd6e9/ao4c03771_0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/f8f35625f2fd/ao4c03771_0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/f96589d3c91d/ao4c03771_0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/434c5365283a/ao4c03771_0008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/c97da04ce518/ao4c03771_0009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/4cb148c157d3/ao4c03771_0010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/bc8b223f0eac/ao4c03771_0011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/98c2bc660cc4/ao4c03771_0012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/e8ee15f4edce/ao4c03771_0013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/eebc5c35b740/ao4c03771_0014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/f020eed67884/ao4c03771_0015.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/1e0c7c222ed9/ao4c03771_0016.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/5f80371df099/ao4c03771_0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/38a0a99f416f/ao4c03771_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/05f08a7e67f9/ao4c03771_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/ff62f9bc7734/ao4c03771_0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/62ddf99bd6e9/ao4c03771_0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/f8f35625f2fd/ao4c03771_0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/f96589d3c91d/ao4c03771_0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/434c5365283a/ao4c03771_0008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/c97da04ce518/ao4c03771_0009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/4cb148c157d3/ao4c03771_0010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/bc8b223f0eac/ao4c03771_0011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/98c2bc660cc4/ao4c03771_0012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/e8ee15f4edce/ao4c03771_0013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/eebc5c35b740/ao4c03771_0014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/f020eed67884/ao4c03771_0015.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e91/11270720/1e0c7c222ed9/ao4c03771_0016.jpg

相似文献

1
Pressurized Hot Water Extraction as Green Technology for Natural Products as Key Technology with Regard to Hydrodistillation and Solid-Liquid Extraction.加压热水萃取作为天然产物的绿色技术——相对于水蒸馏和固液萃取的关键技术
ACS Omega. 2024 Jul 10;9(29):31998-32010. doi: 10.1021/acsomega.4c03771. eCollection 2024 Jul 23.
2
Green Manufacturing for Herbal Remedies with Advanced Pharmaceutical Technology.采用先进制药技术的草药制剂绿色制造。
Pharmaceutics. 2023 Jan 5;15(1):188. doi: 10.3390/pharmaceutics15010188.
3
Green Extraction Methods for Polyphenols from Plant Matrices and Their Byproducts: A Review.植物基质及其副产品中多酚的绿色提取方法：综述
Compr Rev Food Sci Food Saf. 2017 Mar;16(2):295-315. doi: 10.1111/1541-4337.12253. Epub 2017 Jan 12.
4
Valorisation of branches as a raw product with green technology extraction methods.采用绿色技术提取方法将树枝作为原材料进行增值利用。
Curr Res Food Sci. 2019 Dec 5;2:20-24. doi: 10.1016/j.crfs.2019.11.006. eCollection 2020 Jun.
5
Advanced analytical techniques for the extraction and characterization of plant-derived essential oils by gas chromatography with mass spectrometry.采用气相色谱-质谱联用技术提取和表征植物源精油的先进分析技术。
J Sep Sci. 2015 Feb;38(3):483-501. doi: 10.1002/jssc.201400724. Epub 2015 Jan 2.
6
Sustainable Green Extraction of Carotenoid Pigments: Innovative Technologies and Bio-Based Solvents.类胡萝卜素色素的可持续绿色提取：创新技术与生物基溶剂
Antioxidants (Basel). 2024 Feb 15;13(2):239. doi: 10.3390/antiox13020239.
7
Sono hydrodistillation for isolation of citronella oil: A symbiotic effect of sonication and hydrodistillation towards energy efficiency and environment friendliness.超声协同水蒸馏提取香茅油：超声与水蒸馏协同作用提高能效和环境友好性。
Ultrason Sonochem. 2018 Dec;49:145-153. doi: 10.1016/j.ultsonch.2018.07.038. Epub 2018 Jul 29.
8
Green extraction of natural products: concept and principles.天然产物的绿色提取：概念与原理
Int J Mol Sci. 2012;13(7):8615-8627. doi: 10.3390/ijms13078615. Epub 2012 Jul 11.
9
Multiscale Process Intensification of Waste Valorization Reactions.废物增值反应的多尺度过程强化
Acc Chem Res. 2023 Oct 3;56(19):2606-2619. doi: 10.1021/acs.accounts.3c00364. Epub 2023 Sep 15.
10
Sustainable approaches to analyzing phenolic compounds: a green chemistry perspective.分析酚类化合物的可持续方法：绿色化学视角
Anal Sci. 2024 Nov;40(11):1947-1968. doi: 10.1007/s44211-024-00640-5. Epub 2024 Aug 6.

本文引用的文献

1
Disclosing the potential of Cupressus leylandii A.B. Jacks & Dallim, Eucalyptus globulus Labill., Aloysia citrodora Paláu, and Melissa officinalis L. hydrosols as eco-friendly antimicrobial agents.揭示莱兰柏、蓝桉、柠檬罗勒和香蜂草纯露作为环保型抗菌剂的潜力。
Nat Prod Bioprospect. 2024 Jan 2;14(1):1. doi: 10.1007/s13659-023-00417-9.
2
Hot-Water Hemicellulose Extraction from Fruit Processing Residues.从水果加工残渣中提取热水半纤维素
ACS Omega. 2022 Apr 12;7(16):13436-13447. doi: 10.1021/acsomega.1c06055. eCollection 2022 Apr 26.
3
Digital Twins in Biomanufacturing.
数字孪生在生物制造中的应用。
Adv Biochem Eng Biotechnol. 2021;176:181-262. doi: 10.1007/10_2020_146.
4
Plants-Derived Biomolecules as Potent Antiviral Phytomedicines: New Insights on Ethnobotanical Evidences against Coronaviruses.植物源生物分子作为有效的抗病毒植物药：关于抗冠状病毒民族植物学证据的新见解
Plants (Basel). 2020 Sep 21;9(9):1244. doi: 10.3390/plants9091244.
5
Lignin-Rich PHWE Hemicellulose Extracts Responsible for Extended Emulsion Stabilization.富含木质素的超临界水萃取半纤维素提取物对延长乳液稳定性起作用。
Front Chem. 2019 Dec 17;7:871. doi: 10.3389/fchem.2019.00871. eCollection 2019.
6
Development of Improved Vaccine Adjuvants Based on the Saponin Natural Product QS-21 through Chemical Synthesis.基于天然产物 QS-21 皂苷的改良疫苗佐剂的化学合成。
Acc Chem Res. 2016 Sep 20;49(9):1741-56. doi: 10.1021/acs.accounts.6b00242. Epub 2016 Aug 28.
7
High performance curcumin subcritical water extraction from turmeric (Curcuma longa L.).从姜黄（Curcuma longa L.）中高效提取姜黄素的亚临界水萃取法。
J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Jun 1;1022:191-198. doi: 10.1016/j.jchromb.2016.04.021. Epub 2016 Apr 12.
8
Natural Products as Sources of New Drugs from 1981 to 2014.1981年至2014年作为新药来源的天然产物
J Nat Prod. 2016 Mar 25;79(3):629-61. doi: 10.1021/acs.jnatprod.5b01055. Epub 2016 Feb 7.
9
Extraction characteristics of subcritical water depending on the number of hydroxyl group in flavonols.取决于黄酮醇中羟基数量的亚临界水提取特性
Food Chem. 2015 Feb 1;168:21-6. doi: 10.1016/j.foodchem.2014.07.047. Epub 2014 Jul 14.
10
Pressurized hot water extraction (PHWE).加压热水萃取（PHWE）。
J Chromatogr A. 2010 Apr 16;1217(16):2484-94. doi: 10.1016/j.chroma.2009.12.050. Epub 2010 Jan 4.