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全身低温随机试验在足月缺氧缺血性脑病中对MRI上的皮质有选择性保护作用。

Randomized trial of systemic hypothermia selectively protects the cortex on MRI in term hypoxic-ischemic encephalopathy.

作者信息

Inder Terrie E, Hunt Rod W, Morley Colin J, Coleman Lee, Stewart Michael, Doyle Lex W, Jacobs Susan E

机构信息

Division of Newborn Services, Royal Women's Hospital, Neonatal Neurology, Royal Children's Hospital, Melbourne, Australia.

出版信息

J Pediatr. 2004 Dec;145(6):835-7. doi: 10.1016/j.jpeds.2004.07.034.

DOI:10.1016/j.jpeds.2004.07.034
PMID:15580212
Abstract

Twenty-six infants with hypoxic-ischemic encephalopathy (HIE) were randomized to normothermia or to systemic hypothermia. The hypothermia group had less cortical gray matter signal abnormality on magnetic resonance imaging (MRI) (1/12 vs 7/14 infants in the normothermic group; P = .036), which may indicate differing regional benefit from systemic hypothermia.

摘要

26名患有缺氧缺血性脑病(HIE)的婴儿被随机分为正常体温组或全身低温治疗组。低温治疗组在磁共振成像(MRI)上皮质灰质信号异常较少(低温治疗组1/12例婴儿,正常体温组7/14例婴儿;P = 0.036),这可能表明全身低温治疗在不同区域有不同的益处。

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