工作压力与新诊断纤维肌痛的发病率：前瞻性队列研究
Work stress and incidence of newly diagnosed fibromyalgia: prospective cohort study.
作者信息
Kivimäki Mika, Leino-Arjas Päivi, Virtanen Marianna, Elovainio Marko, Keltikangas-Järvinen Liisa, Puttonen Sampsa, Vartia Maarit, Brunner Eric, Vahtera Jussi
机构信息
Department of Psychology, University of Helsinki, P.O. Box 9, FIN-00014, Helsinki, Finland.
出版信息
J Psychosom Res. 2004 Nov;57(5):417-22. doi: 10.1016/j.jpsychores.2003.10.013.
OBJECTIVES
We examined the prospective association between occupational stress and incidence of newly diagnosed fibromyalgia.
METHODS
Cohort study with questionnaire surveys in 1998 and 2000 completed by 4791 hospital employees (4250 women and 541 men). Stress, as indicated by high workload, low decision latitude, and being a victim of workplace bullying, was assessed in the first survey. Incident cases (n=47) were employees reporting physician-diagnosed fibromyalgia in 2000 but not in 1998. Covariates were sex, age, income, obesity, and smoking.
RESULTS
After adjustment for covariates, the odds ratio of incident diagnosed fibromyalgia for workplace bullying was 4.1 (95% CI 2.0-9.6). The corresponding odds ratios for high workload and low decision latitude were 2.1 (1.2-3.9) and 2.1 (1.1-4.0), respectively.
CONCLUSION
Stress seems to be a contributing factor in the development of fibromyalgia, but further research is needed to examine whether stress perceptions are affected by undiagnosed fibromyalgia.
目的
我们研究了职业压力与新诊断纤维肌痛发病率之间的前瞻性关联。
方法
对4791名医院员工（4250名女性和541名男性）进行队列研究，并于1998年和2000年进行问卷调查。在首次调查中评估了高工作量、低决策自由度以及遭受职场欺凌所表明的压力情况。确诊病例（n = 47）为在2000年报告经医生诊断患有纤维肌痛但在1998年未患该病的员工。协变量包括性别、年龄、收入、肥胖和吸烟情况。
结果
在对协变量进行调整后，职场欺凌导致新诊断纤维肌痛的比值比为4.1（95%可信区间2.0 - 9.6）。高工作量和低决策自由度对应的比值比分别为2.1（1.2 - 3.9）和2.1（1.1 - 4.0）。
结论
压力似乎是纤维肌痛发病的一个促成因素，但需要进一步研究以检验压力认知是否受未确诊的纤维肌痛影响。
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