Mäki K, Vahtera J, Virtanen M, Elovainio M, Keltikangas-Järvinen L, Kivimäki M
Department of Psychology, University of Helsinki, Helsinki, Finland.
Cephalalgia. 2008 Jan;28(1):18-25. doi: 10.1111/j.1468-2982.2007.01462.x. Epub 2007 Oct 23.
This prospective cohort study examined whether work stress, as indicated by the job strain model and the effort-reward imbalance model, predicts new-onset migraine among 19,469 female employees with no history of migraine at study entry. A baseline survey between 2000 and 2002 assessed work stress and demographic factors. Self-reported newly diagnosed migraine was measured at follow-up between 2004 and 2005 and 1281 new cases of migraine were detected. In logistic regression analysis adjusted for age, socioeconomic position and depression at baseline, no association between job strain and migraine was found. In contrast, high effort-reward imbalance was associated with slightly increased risk of migraine at follow-up, odds ratio 1.23 (95% confidence interval 1.04, 1.45). The proportion of new migraine cases attributable to high effort-reward imbalance was 6.2%. If the observed association is causal, our findings suggest that high effort-reward imbalance might function as a modifiable risk factor for new-onset migraine.
这项前瞻性队列研究调查了由工作要求-控制模型和付出-回报失衡模型所表明的工作压力，是否能预测19469名在研究开始时无偏头痛病史的女性员工中新发偏头痛的情况。2000年至2002年期间进行的一项基线调查评估了工作压力和人口统计学因素。在2004年至2005年的随访中测量了自我报告的新诊断偏头痛情况，共检测到1281例新的偏头痛病例。在对年龄、社会经济地位和基线时的抑郁情况进行校正的逻辑回归分析中，未发现工作要求-控制与偏头痛之间存在关联。相比之下，高付出-回报失衡与随访时偏头痛风险略有增加相关，比值比为1.23（95%置信区间为1.04, 1.45）。高付出-回报失衡导致的新发偏头痛病例比例为6.2%。如果观察到的关联是因果关系，我们的研究结果表明，高付出-回报失衡可能是新发偏头痛的一个可改变的风险因素。
