基底细胞癌和鳞状细胞癌的手术切除切缘

Surgical margins of excision for basal cell carcinoma and squamous cell carcinoma.

作者信息

Huang Conway C, Boyce Sarah M

机构信息

University of Alabama at Birmingham, Birmingham, AL, USA.

出版信息

Semin Cutan Med Surg. 2004 Sep;23(3):167-73. doi: 10.1016/j.sder.2004.06.002.

DOI:10.1016/j.sder.2004.06.002

PMID:15584682

Abstract

In excising basal and squamous cell carcinomata, the surgical margin that is wide enough to completely remove the tumor an acceptable percentage of the time and narrow enough to minimize removal of excessive normal tissue must be selected. This task can be reliably accomplished with comprehensive knowledge of factors that affect subclinical tumor extension such as tumor appearance, diameter, histology, location, treatment status, and, in the case of squamous cell carcinoma, vertical invasion depth and involvement of subcutaneous fat. Information regarding these factors along with specific recommendations about excisional margins for basal cell and squamous cell carcinomata is presented.

摘要

在切除基底细胞癌和鳞状细胞癌时，必须选择足够宽的手术切缘，以便在可接受的比例下完全切除肿瘤，同时又要足够窄，以尽量减少正常组织的过度切除。借助对影响亚临床肿瘤扩展的因素的全面了解，如肿瘤外观、直径、组织学、位置、治疗状况，以及对于鳞状细胞癌而言的垂直浸润深度和皮下脂肪受累情况，这项任务能够可靠地完成。本文介绍了有关这些因素的信息以及关于基底细胞癌和鳞状细胞癌切除切缘的具体建议。