Soeder B M, Urbach H, Elger C E, Bien C G, Beyenburg S
Klinik für Epileptologie, Universität Bonn.
Nervenarzt. 2005 Jun;76(6):760-2. doi: 10.1007/s00115-004-1844-y.
Since the initial description of limbic encephalitis (LE) in 1960/1968, several subforms of this clinico-neuropathological syndrome have been identified. The best known is paraneoplastic LE. However, non-paraneoplastic forms have been reported, too. Very recently, autoantibodies against voltage-gated potassium channels have been described in association with LE. The diagnostic workup of such a case and the apparently typical good response to long-term immunotherapy of this LE subform are described.
自1960年/1968年首次描述边缘叶脑炎（LE）以来，已确定了该临床神经病理综合征的几种亚型。最广为人知的是副肿瘤性LE。然而，也有非副肿瘤性形式的报道。最近，已描述了与LE相关的针对电压门控钾通道的自身抗体。本文描述了此类病例的诊断检查以及这种LE亚型对长期免疫治疗明显典型的良好反应。
