Lamey Philip-John, Freeman Ruth, Eddie Sally-Anne, Pankhurst Caroline, Rees Terry
School of Dentistry, Queen's University, Belfast, Northern Ireland.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005 Jan;99(1):48-54. doi: 10.1016/j.tripleo.2004.01.021.
To investigate if burning mouth syndrome (BMS) patients have differing health perceptions, medication, and life experiences compared with controls and to examine the role of vulnerability factors and differentiate them from the presenting symptomology in patients with BMS.
A nonprobability convenience sample of patients presenting with BMS and age- and sex-matched controls were recruited from Queen's University, Belfast, King's College London, and Baylor College of Dentistry, Dallas. Participants completed a questionnaire to assess 9 aspects of their medical and social history, including early and past life experiences. The subjects completed the Hospital Anxiety and Depression Scale to assess current distress.
Participants with BMS had significantly higher experiences of adverse early life experiences compared with controls. They had statistically significantly higher mean scores for anxiety and depression compared with controls. A hierarchical multiple logistic regression analysis showed that the characteristics of BMS included cancer phobia, gastro-intestinal problems, and chronic fatigue.
BMS is a complex disorder. People who experience adverse life experiences may become vulnerable to developing BMS in later life.
调查灼口综合征（BMS）患者与对照组相比在健康认知、用药及生活经历方面是否存在差异，并研究脆弱因素在BMS患者中的作用，以及将这些因素与BMS患者的现有症状区分开来。
从贝尔法斯特女王大学、伦敦国王学院和达拉斯贝勒牙科学院招募了出现BMS症状的患者以及年龄和性别匹配的对照组，组成非概率便利样本。参与者完成了一份问卷，以评估其医疗和社会历史的9个方面，包括早期和过去的生活经历。受试者完成医院焦虑抑郁量表以评估当前的痛苦程度。
与对照组相比，BMS患者有更高比例的不良早期生活经历。与对照组相比，他们在焦虑和抑郁方面的平均得分在统计学上显著更高。分层多元逻辑回归分析表明，BMS的特征包括恐癌、胃肠道问题和慢性疲劳。
BMS是一种复杂的疾病。经历过不良生活经历的人在晚年可能更容易患上BMS。
