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[人类子宫和输卵管妊娠前3个月绒毛膜多糖的比较特征]

[Comparative characteristics of villous chorionic polysaccharides during the first 3 months of human uterine and tubal pregnancy].

作者信息

Gromokovskaia T S

出版信息

Arkh Anat Gistol Embriol. 1979 Apr;76(4):71-6.

PMID:156016
Abstract

Qualitative composition of polysaccharides has been studied in 100 chorions of human fetuses, 3.5--12 weeks of embryonic development, 40 of them have been obtained from tubal pregnansies. It has been stated that in villous stroma of the tubal pregnancy at the 4--5th week of gestation, sulphate polysaccharides appear that demonstrates an earlier maturation of villi at this type of pregnancy. It is possible that in the formation of intracellular substance of the villous stroma together with fibroblasts Kastschenko -- Hoffbauer's cells also participate. A characteristic feature for the tubal pregnancy is the appearance of distrophically changed villi beginning from the 4th week of gestation. In plasmodiotrophoblast of such villi the amount of Hale-positive and PAS-positive substances is sharply decreasing, and neutral polysaccharides, chondroitin-4-sulfate, chondroitin-6-sulfate and dermatan-sulfate (small amount) are intensively accumulating in the stroma.

摘要

对100例妊娠3.5 - 12周的人类胎儿绒毛膜的多糖定性组成进行了研究,其中40例取自输卵管妊娠。研究表明,在妊娠第4 - 5周的输卵管妊娠绒毛间质中,出现了硫酸化多糖,这表明此类妊娠时绒毛成熟较早。绒毛间质细胞内物质的形成可能有卡斯琴科 - 霍夫鲍尔细胞和成纤维细胞共同参与。输卵管妊娠的一个特征是从妊娠第4周开始出现营养不良性改变的绒毛。在这类绒毛的合体滋养层中, Hale阳性和PAS阳性物质的量急剧减少,而中性多糖、硫酸软骨素 - 4、硫酸软骨素 - 6和硫酸皮肤素(少量)在间质中大量积聚。

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