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Vector NTI,一款功能全面的一体化序列分析套件。

Vector NTI, a balanced all-in-one sequence analysis suite.

作者信息

Lu Guoqing, Moriyama Etsuko N

机构信息

School of Biological Sciences and Center for Biotechnology, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.

出版信息

Brief Bioinform. 2004 Dec;5(4):378-88. doi: 10.1093/bib/5.4.378.

Abstract

Vector NTI is a well-balanced desktop application integrated for molecular sequence analysis and biological data management. It has a centralised database and five application modules: Vector NTI, AlignX, BioAnnotator, ContigExpress and GenomBench. In this review, the features and functions available in this software are examined. These include database management, primer design, virtual cloning, alignments, sequence assembly, 3D molecular viewer and internet tools. Some problems encountered when using this software are also discussed. It is hoped that this review will introduce this software to more molecular biologists so they can make better-informed decisions when choosing computational tools to facilitate their everyday laboratory work. This tool can save time and enhance analysis but it requires some learning on the user's part and there are some issues that need to be addressed by the developer.

摘要

Vector NTI是一款集成了分子序列分析和生物数据管理功能的平衡良好的桌面应用程序。它有一个集中式数据库和五个应用模块:Vector NTI、AlignX、BioAnnotator、ContigExpress和GenomBench。在这篇综述中,对该软件的特性和功能进行了研究。这些包括数据库管理、引物设计、虚拟克隆、比对、序列组装、3D分子查看器和网络工具。还讨论了使用该软件时遇到的一些问题。希望这篇综述能向更多分子生物学家介绍这款软件,以便他们在选择计算工具以方便日常实验室工作时能做出更明智的决策。这个工具可以节省时间并增强分析能力,但用户需要进行一些学习,并且有一些问题需要开发者解决。

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