考虑多个贡献者和群体亚结构的重复测量DNA证据的解释。
Interpretation of repeat measurement DNA evidence allowing for multiple contributors and population substructure.
作者信息
Curran J M, Gill P, Bill M R
机构信息
Department of Statistics, University of Waikato, Private Bag 3105, Hamilton, New Zealand.
出版信息
Forensic Sci Int. 2005 Feb 10;148(1):47-53. doi: 10.1016/j.forsciint.2004.04.077.
Due to the circumstances in some forensic cases, very small amounts of DNA (<100 pg) may be obtained. This, in turn, may affect the reliability of the PCR process, and so it may be advisable to repeat the amplification process for confirmatory purposes. Gill et al. [Forensic Sci. Int. 112 (2000) 17] proposed a method for the statistical evaluation of the PCR replicate information. In this paper we formalize the method proposed by Gill et al. [Forensic Sci. Int. 112 (2000) 17], and extend it to allow for cases involving mixed stains and for population substructure.
由于某些法医案件的情况，可能会获得极少量的DNA（<100 pg）。这反过来可能会影响PCR过程的可靠性，因此为了确认目的重复扩增过程可能是可取的。吉尔等人[《法医学国际》112（2000）17]提出了一种用于PCR重复信息统计评估的方法。在本文中，我们将吉尔等人[《法医学国际》112（2000）17]提出的方法形式化，并将其扩展以适用于涉及混合污渍和群体亚结构的情况。
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