Fernandez-Ricaud Luciano, Warringer Jonas, Ericson Elke, Pylvänäinen Ilona, Kemp Graham J L, Nerman Olle, Blomberg Anders
Department of Cell and Molecular Biology, Lundberg Laboratory, Göteborg University Medicinaregatan 9c, 41390 Göteborg, Sweden.
Nucleic Acids Res. 2005 Jan 1;33(Database issue):D369-73. doi: 10.1093/nar/gki126.
The rapid recent evolution of the field phenomics--the genome-wide study of gene dispensability by quantitative analysis of phenotypes--has resulted in an increasing demand for new data analysis and visualization tools. Following the introduction of a novel approach for precise, genome-wide quantification of gene dispensability in Saccharomyces cerevisiae we here announce a public resource for mining, filtering and visualizing phenotypic data--the PROPHECY database. PROPHECY is designed to allow easy and flexible access to physiologically relevant quantitative data for the growth behaviour of mutant strains in the yeast deletion collection during conditions of environmental challenges. PROPHECY is publicly accessible at http://prophecy.lundberg.gu.se.
表型组学领域（通过对表型进行定量分析来开展全基因组范围的基因必需性研究）最近发展迅速，这导致对新的数据分析和可视化工具的需求日益增加。在引入一种用于精确地全基因组定量分析酿酒酵母基因必需性的新方法之后，我们在此宣布一个用于挖掘、筛选和可视化表型数据的公共资源——PROPHECY数据库。PROPHECY旨在便于灵活获取与酵母缺失文库中突变菌株在环境挑战条件下生长行为相关的生理学定量数据。可通过http://prophecy.lundberg.gu.se公开访问PROPHECY。
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