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[颅内动脉瘤破裂。基于患者意识状态和年龄的手术方法改良。对两个时期(1972 - 1984年和1985 - 1989年)收治的468例患者的个人经验]

[Ruptured intracranial aneurysm. Modification of the surgical method based on the state of consciousness and age of patients. Personal experience with 468 patients admitted during 2 periods (1972-84 and 1985-89)].

作者信息

Deruty R, Mottolese C, Pelissou-Guyotat I, Bognar L, Oubouklik A

机构信息

Hôpital neurologique, Lyon.

出版信息

Neurochirurgie. 1992;38(1):9-17.

PMID:1560889
Abstract

The management of the ruptured intracranial aneurysm (clinical grade I to IV only) is studied in a series including 140 patients admitted from 1985 through 1989, in which selected patients were submitted to early surgery and other patients were postponed for delayed surgery. The results are compared to those of an earlier series including 328 patients admitted from 1972 through 1984, for which the general attitude was the delayed surgery: in the later series; the selection for the timing of surgery was based on two main parameters: the clinical status and the patient's age. When we compare both series, the overall management results demonstrate an improvement of 10% of satisfactory results and a decrease of 10% in the death rate in favour of the later series; for the surgical results, the figures are respectively 6% and 5% in favour of the later series. The relationship between age and outcome shows a considerable improvement: over 50 years of age, we observed plus 25% of satisfactory results and minus 22% in death in favour of the later series. Similarly, the relationship between state of consciousness and outcome, demonstrated a great improvement: for drowsy and stuporous patients the figures are respectively plus 22% and minus 21% in favour of the later series. When we consider the later series alone, the patients were admitted at 4 intervals of time from S.A.H. (D0-3, D4-6, D7-15, D16 and over). The most favorable outcome was observed for those patients admitted late (after D7) and already stabilized.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

对1985年至1989年收治的140例颅内动脉瘤破裂患者(仅临床分级为I至IV级)的治疗进行了研究,其中部分患者接受早期手术,其他患者则延期进行延迟手术。将结果与1972年至1984年收治的328例患者的早期系列结果进行比较,早期系列的总体治疗态度是延迟手术:在后期系列中,手术时机的选择基于两个主要参数:临床状态和患者年龄。当我们比较这两个系列时,总体治疗结果显示,后期系列的满意结果提高了10%,死亡率降低了10%;就手术结果而言,后期系列的数字分别为6%和5%。年龄与预后的关系显示出相当大的改善:50岁以上患者,后期系列的满意结果增加了25%,死亡减少了22%。同样,意识状态与预后的关系也显示出很大改善:对于嗜睡和昏迷患者,后期系列的数字分别为增加22%和减少21%。仅考虑后期系列时,患者在蛛网膜下腔出血后的4个时间段入院(D0 - 3、D4 - 6、D7 - 15、D16及以后)。对于晚期(D7之后)入院且病情已稳定的患者,观察到的预后最为良好。(摘要截断于250字)

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