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[过去20年的相同问题:颅内动脉瘤破裂后何时应进行手术治疗?(434例经验)]

[The same question for the past 20 years: when should a ruptured intracranial aneurysm be surgically treated? (Experience with 434 cases)].

作者信息

Deruty R, Mottolese C

机构信息

Hopital neurologique, Lyon.

出版信息

Agressologie. 1990 Jun;31(6):329-35.

PMID:2285102
Abstract

The timing of surgery for the ruptured aneurysm (SAH) remains controversial. After the period of delayed surgery, the early surgery is now more and more frequently advocated. This paper, study our experience in aneurysm surgery in two different periods, considering only patients admitted in grades I to IV, excluding grade V patients (deep coma, decerebration). During the former period (1972-1984) 328 patients were admitted and considered for delayed surgery, usually during the second week following SAH. 94.5% of patients were operated upon. 5.5% patients died before surgery, from ischemia (3%) or from rebleeding (2.5%). 38.5% were admitted between (D.O-D3) after SAH, D.O being the day of SAH. Only 5.7% were operated upon between D.O-D3. The higher peak of surgery was during the second week (41.8%) and during the third week (39.2%). During the later period (1985-1988) 106 patients were admitted, 50% of them between D.O and D3 after SAH. Every patient was operated upon. The patients admitted between D.O and D3 were operated upon as follows: between D.O and D3 = 32.1%, between D4 and D6 = 22.6%, between D7 and D15 = 34%, after D16 = 11.3%. The analysis of these sub-groups demonstrates that the distribution was related to the age and clinical status. Patients being awake and under 50 years of age were considered for early surgery. Patients being obnubilated or stuporous, and over 50 years of age were planned for delayed surgery. Angiographic spasm and extension of blood in CT Scan were taken in consideration to a lesser degree.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

破裂性动脉瘤(蛛网膜下腔出血)的手术时机仍存在争议。在延迟手术时期之后,早期手术现在越来越多地被提倡。本文研究了我们在两个不同时期进行动脉瘤手术的经验,仅考虑I至IV级入院患者,不包括V级患者(深度昏迷、去脑强直)。在前一时期(1972 - 1984年),328例患者入院并考虑进行延迟手术,通常在蛛网膜下腔出血后的第二周。94.5%的患者接受了手术。5.5%的患者在手术前死亡,死于缺血(3%)或再出血(2.5%)。38.5%的患者在蛛网膜下腔出血后(D.O - D3)入院,D.O为蛛网膜下腔出血当天。只有5.7%的患者在D.O - D3期间接受手术。手术的较高峰值出现在第二周(41.8%)和第三周(39.2%)。在后一时期(1985 - 1988年),106例患者入院,其中50%在蛛网膜下腔出血后的D.O和D3之间。每位患者都接受了手术。在D.O和D3之间入院的患者手术情况如下:D.O和D3之间 = 32.1%,D4和D6之间 = 22.6%,D7和D15之间 = 34%,D16之后 = 11.3%。对这些亚组的分析表明,分布与年龄和临床状况有关。清醒且年龄在50岁以下的患者考虑早期手术。意识模糊或昏迷且年龄超过50岁的患者计划进行延迟手术。血管造影痉挛和CT扫描中血液的扩展在考虑因素中所占程度较小。(摘要截断于250字)

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