Scharf Steven M, Seiden Lawrence, DeMore Jennifer, Carter-Pokras Olivia
Sleep Disorders Center, Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Maryland Medical Center, Baltimore, Maryland 21201-1102, USA.
Sleep Breath. 2004 Dec;8(4):173-83. doi: 10.1007/s11325-004-0173-5.
We characterized differences in severity, presentation, and treatment compliance in sleep-disordered breathing (SDB) between African Americans (AA) and Caucasians (W). We retrospectively analyzed demographics, proxy measures of socioeconomic position, concurrent illness, presenting complaints, polysomnographic data including respiratory disturbance index (RDI) and time less than 90% O2 saturation (T90), and acceptance of and long-term compliance with CPAP therapy. Over 1 year there were 128 AA, 102 W, and 3 "other." AA were younger (44.9+/-14.1 vs. 49.2+/-14.5 years; P=0.022), had greater body mass index (BMI) (39.7+/-10.7 vs. 33.4+/-9.2 kg/m2; p<0.0001), and reported lower estimated median household income (MHI) than W ($33,365+/-15,236 vs. $52,641+/-20,209; p<0.0001). OSA was more severe among AA: (median RDI: AA 32.9, W 29.1 events/h; p=0.008; median T90: AA 17.6 vs. W 5.3 per minute; P=0.006). However, after adjustment for BMI and MHI, differences between AA and W in RDI were not significant. Equal frequencies of AA and W accepted and were compliant with CPAP. We conclude that while AA present with more severe OSA than W this was accounted for by factors known to influence OSA severity. Further, there were no racial differences in accepting and adhering to therapy with CPAP.
我们对非裔美国人（AA）和白种人（W）在睡眠呼吸障碍（SDB）的严重程度、症状表现及治疗依从性方面的差异进行了特征描述。我们回顾性分析了人口统计学数据、社会经济地位的替代指标、并发疾病、主诉、多导睡眠图数据（包括呼吸紊乱指数（RDI）和低于90%氧饱和度的时间（T90））以及对持续气道正压通气（CPAP）治疗的接受情况和长期依从性。在1年多的时间里，有128名非裔美国人、102名白种人和3名“其他种族”。非裔美国人更年轻（44.9±14.1岁 vs. 49.2±14.5岁；P = 0.022），体重指数（BMI）更高（39.7±10.7 vs. 33.4±9.2 kg/m²；p < 0.0001），且报告的估计家庭收入中位数（MHI）低于白种人（33,365±15,236美元 vs. 52,641±20,209美元；p < 0.0001）。阻塞性睡眠呼吸暂停（OSA）在非裔美国人中更为严重：（RDI中位数：非裔美国人32.9，白种人29.1次/小时；p = 0.008；T90中位数：非裔美国人每分钟17.6次 vs. 白种人每分钟5.3次；P = 0.006）。然而，在对BMI和MHI进行调整后，非裔美国人和白种人在RDI上的差异并不显著。非裔美国人和白种人接受并依从CPAP治疗的频率相同。我们得出结论，虽然非裔美国人的OSA比白种人更严重，但这是由已知影响OSA严重程度的因素所致。此外，在接受和坚持CPAP治疗方面没有种族差异。
