Li Jiashen, Mak Arthur F T
Jockey Club Rehabilitation Engineering Center, The Hong Kong Polytechnic University, Hong Hum, Kowloon, Hong Kong, The People's Republic of China.
J Biomater Appl. 2005 Jan;19(3):253-66. doi: 10.1177/0885328205047219.
Using a simple experimental setup, the hydraulic permeability of fibrous nonwoven polyglycolic acid (PGA) scaffolds is studied after different degradation durations in PBS. The hydraulic permeability of the scaffolds increased with the degradation time. After being incubated for about 4 weeks, the permeability of the scaffold begins to drop. It is noted that the PGA scaffold apparently begins to contract and cannot maintain its original shape after 4 weeks of degradation. These results underpin the understanding of the biotransport processes in the scaffolds during tissue engineering experiments.
采用简单的实验装置，研究了纤维状非织造聚乙醇酸（PGA）支架在PBS中不同降解时间后的水力渗透性。支架的水力渗透性随降解时间增加。孵育约4周后，支架的渗透性开始下降。值得注意的是，PGA支架在降解4周后明显开始收缩，无法维持其原始形状。这些结果有助于理解组织工程实验中支架内的生物传输过程。
