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吻合器痔上黏膜环切术与传统痔切除术的比较:随机对照试验的系统评价

Stapled hemorrhoidopexy compared with conventional hemorrhoidectomy: systematic review of randomized, controlled trials.

作者信息

Nisar Pasha J, Acheson Austin G, Neal Keith R, Scholefield John H

机构信息

Section of Surgery, University Hospital, Queen's Medical Centre, Nottingham, United Kingdom.

出版信息

Dis Colon Rectum. 2004 Nov;47(11):1837-45. doi: 10.1007/s10350-004-0679-8.

Abstract

PURPOSE

This study was designed to determine whether conventional hemorrhoidectomy or stapled hemorrhoidopexy is superior for the management of hemorrhoids.

METHODS

A systematic review of all randomized trials comparing conventional hemorrhoidectomy with stapled hemorrhoidopexy was performed. MEDLINE, EMBASE, and Cochrane Library databases were searched using the terms "hemorrhoid*" or "haemorrhoid*" and "stapl*." A list of clinical outcomes was extracted. Meta-analysis was calculated if possible.

RESULTS

Fifteen trials recruiting 1,077 patients were included. Follow-up ranged from 6 weeks to 37 months. Qualitative analysis showed that stapled hemorrhoidopexy is less painful compared with hemorrhoidectomy. Stapled hemorrhoidopexy has a shorter inpatient stay (weighted mean difference, -1.02 days; 95 percent confidence interval, -1.47 to -0.57; P = 0.0001), operative time (weighted mean difference, -12.82 minutes; 95 percent confidence interval, -22.61 to -3.04; P = 0.01), and return to normal activity (standardized mean difference, -4.03 days; 95 percent confidence interval, -6.95 to -1.10; P = 0.007). Studies in a day-case setting do not prove that stapled hemorrhoidopexy is more feasible than conventional hemorrhoidectomy. Stapled hemorrhoidopexy has a higher recurrence rate (odds ratio, 3.64; 95 percent confidence interval, 1.40-9.47; P = 0.008) at a minimum follow-up of six months.

CONCLUSIONS

Although stapled hemorrhoidopexy is widely used, the data available on long-term outcomes is limited. The variability in case selection and reported end points are difficulties in interpreting results. Stapled hemorrhoidopexy has unique potential complications and is a less effective cure compared with hemorrhoidectomy. With this understanding, it may be offered to patients seeking a less painful alternative to conventional surgery. Hemorrhoidectomy remains the "gold standard" of treatment.

摘要

目的

本研究旨在确定传统痔切除术或吻合器痔上黏膜环切术在痔治疗中哪种更具优势。

方法

对所有比较传统痔切除术与吻合器痔上黏膜环切术的随机试验进行系统评价。使用“hemorrhoid*”或“haemorrhoid*”以及“stapl*”检索MEDLINE、EMBASE和Cochrane图书馆数据库。提取临床结局列表。若可能则进行荟萃分析。

结果

纳入15项试验,共1077例患者。随访时间为6周至37个月。定性分析表明,与痔切除术相比,吻合器痔上黏膜环切术疼痛较轻。吻合器痔上黏膜环切术的住院时间较短(加权平均差,-1.02天;95%置信区间,-1.47至-0.57;P = 0.0001)、手术时间较短(加权平均差,-12.82分钟;95%置信区间,-22.61至-3.04;P = 0.01),恢复正常活动时间较短(标准化平均差,-4.03天;95%置信区间,-6.95至-1.10;P = 0.007)。日间手术的研究未证明吻合器痔上黏膜环切术比传统痔切除术更可行。在至少6个月的随访中,吻合器痔上黏膜环切术的复发率较高(优势比,3.64;95%置信区间,1.40 - 9.47;P = 0.008)。

结论

尽管吻合器痔上黏膜环切术被广泛应用,但关于长期结局的可用数据有限。病例选择和报告终点的变异性给结果解读带来困难。吻合器痔上黏膜环切术有独特的潜在并发症,与痔切除术相比治愈效果较差。基于此认识,对于寻求比传统手术疼痛更轻替代方法的患者可提供该术式。痔切除术仍是治疗的“金标准”。

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