• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Large clinical trials in musculoskeletal trauma: are they possible? Lessons learned from the international study of the use of rhBMP-2 in open tibial fractures.

作者信息

Csimma Cristina, Swiontkowski Marc F

机构信息

Wyeth Research, 87 Cambridge Park Drive, Office 3013, Cambridge, MA 02140, USA.

出版信息

J Bone Joint Surg Am. 2005 Jan;87(1):218-22. doi: 10.2106/JBJS.D.01938.

DOI:10.2106/JBJS.D.01938
PMID:15634835
Abstract
摘要

相似文献

1
Large clinical trials in musculoskeletal trauma: are they possible? Lessons learned from the international study of the use of rhBMP-2 in open tibial fractures.肌肉骨骼创伤的大型临床试验：可行吗？从rhBMP-2用于开放性胫骨骨折的国际研究中汲取的经验教训。
J Bone Joint Surg Am. 2005 Jan;87(1):218-22. doi: 10.2106/JBJS.D.01938.
2
Recombinant human bone morphogenetic protein-2 in open tibial fractures. A subgroup analysis of data combined from two prospective randomized studies.重组人骨形态发生蛋白-2用于开放性胫骨骨折。两项前瞻性随机研究合并数据的亚组分析。
J Bone Joint Surg Am. 2006 Jun;88(6):1258-65. doi: 10.2106/JBJS.E.00499.
3
A health economic analysis of the use of rhBMP-2 in Gustilo-Anderson grade III open tibial fractures for the UK, Germany, and France.在英国、德国和法国，使用 rhBMP-2 治疗 Gustilo-Anderson Ⅲ型开放性胫骨骨折的卫生经济学分析。
Injury. 2009 Dec;40(12):1269-75. doi: 10.1016/j.injury.2009.02.007. Epub 2009 Jun 18.
4
Bone morphogenetic proteins in open fractures: past, present, and future.开放性骨折中的骨形态发生蛋白：过去、现在和未来。
Injury. 2009 Dec;40 Suppl 3:S27-31. doi: 10.1016/S0020-1383(09)70008-7.
5
[Cost-benefit analysis of the use of rhBMP-2 in open tibial fractures: savings from a health insurer's perspective].[从健康保险公司角度看重组人骨形态发生蛋白-2用于开放性胫骨骨折的成本效益分析]
Unfallchirurg. 2006 Jun;109(6):463-70. doi: 10.1007/s00113-006-1079-4.
6
Recombinant human bone morphogenetic protein-2 for grade III open segmental tibial fractures from combat injuries in Iraq.重组人骨形态发生蛋白-2用于治疗伊拉克战争伤所致的Ⅲ级开放性胫骨节段性骨折。
J Bone Joint Surg Br. 2008 Aug;90(8):1068-72. doi: 10.1302/0301-620X.90B8.20349.
7
Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures.重组人骨形态发生蛋白-2治疗开放性胫骨骨折
J Bone Joint Surg Am. 2003 Oct;85(10):2049; author replies 2049-50. doi: 10.2106/00004623-200310000-00027.
8
Selection of a control group in BMP clinical studies.
J Bone Joint Surg Am. 2001;83-A Suppl 1(Pt 2):S159-60.
9
OP-1 clinical studies.
J Bone Joint Surg Am. 2001;83-A Suppl 1(Pt 2):S160-1.
10
Recent developments in the use of bone morphogenetic protein in orthopaedic trauma surgery.骨形态发生蛋白在创伤骨科手术中应用的最新进展。
Curr Med Res Opin. 2006;22 Suppl 1:S13-7; S23. doi: 10.1185/030079906X80585.

引用本文的文献

1
Discontinuation and nonpublication analysis of chronic pain randomized controlled trials.慢性疼痛随机对照试验的中止与未发表分析
Pain Rep. 2023 Apr 4;8(3):e1069. doi: 10.1097/PR9.0000000000001069. eCollection 2023 May-Jun.
2
Patient Recruitment System for Clinical Trials: Mixed Methods Study About Requirements at Ten University Hospitals.临床试验患者招募系统：关于十所大学医院需求的混合方法研究
JMIR Med Inform. 2022 Apr 20;10(4):e28696. doi: 10.2196/28696.
3
Recruitment patterns in a large international randomized controlled trial of perioperative care in cancer patients.
在一项针对癌症患者围手术期护理的大型国际随机对照试验中，招募模式。
Trials. 2021 Mar 20;22(1):219. doi: 10.1186/s13063-021-05149-0.
4
Stronger Together in Lab: Multi-Center and Laboratory Spine Studies Are Closer to Publication than Single-Center and Clinical Spine Studies: Snapshot of Annual Meetings of the Spine Society of Europe.实验室中的携手共进：多中心与实验室脊柱研究比单中心与临床脊柱研究更接近发表——欧洲脊柱学会年会快照
Asian Spine J. 2020 Oct;14(5):608-612. doi: 10.31616/asj.2019.0275. Epub 2020 Apr 8.
5
Radiostereometric analysis of the initial stability of internally fixed femoral neck fractures under differential loading.在不同负荷下对内部固定股骨颈骨折初始稳定性的放射立体测量分析。
J Orthop Res. 2019 Jan;37(1):239-247. doi: 10.1002/jor.24150. Epub 2018 Oct 25.
6
Factors associated with clinical trials that fail and opportunities for improving the likelihood of success: A review.与失败的临床试验相关的因素及提高成功可能性的机会：一项综述。
Contemp Clin Trials Commun. 2018 Aug 7;11:156-164. doi: 10.1016/j.conctc.2018.08.001. eCollection 2018 Sep.
7
Are large fracture trials really possible? What we have learned from the randomized controlled damage control study?大型骨折试验真的可行吗？我们从随机对照损伤控制研究中学到了什么？
Eur J Trauma Emerg Surg. 2018 Dec;44(6):917-925. doi: 10.1007/s00068-017-0891-6. Epub 2017 Dec 28.
8
Central coordination as an alternative for local coordination in a multicenter randomized controlled trial: the FAITH trial experience.中心协调作为多中心随机对照试验中局部协调的替代方法：FAITH 试验经验。
Trials. 2012 Jan 8;13:5. doi: 10.1186/1745-6215-13-5.
9
The impact of clinical data on the evaluation of tibial fracture healing.临床数据对胫骨骨折愈合评估的影响。
Trials. 2011 Nov 3;12:237. doi: 10.1186/1745-6215-12-237.
10
Bone morphogenetic protein (BMP) for fracture healing in adults.用于成人骨折愈合的骨形态发生蛋白（BMP）
Cochrane Database Syst Rev. 2010 Jun 16;2010(6):CD006950. doi: 10.1002/14651858.CD006950.pub2.