Ayala A R, Cervera Aguilar R, Tovar Rodríguez J M, Romo L M, Risco Cortes R, Vargas Martínez C
Dirección de Investigación y Enseñanza, nuevo Hospital Juárez de México, SSA, México, D.F.
Ginecol Obstet Mex. 1992 Feb;60:51-4.
An alteration upon the daily rhythm of blood pressure in patients with gestational hypertension has been reported, albeit inconsistently. Hence we have evaluated the daily rhythm of blood pressure in women with normal gestation (n = 100) and with pregnancy associated hypertension (n = 111). In an attempt to delineate a possible etiology of the hypertension, patients were subdivided according to a classification of the American College of Obstetricians and Gynecologists. (Group I. Preeclampsia-eclampsia; group II. Chronic hypertension; group III. Chronic hypertension with superimposed preeclampsia; group IV. Late gestational hypertension). Blood pressure quantitation was made with sphygmomanometer and by different observes. Those with normal pregnancy showed a higher increase in both systolic and diastolic pressure in the morning with a peak at 1200 H, that contrasted with a very low level registered at 2400 H. Altogether the hypertensive group exhibited a loss of rhythm; whereas by group: in I. There was absence of rhythm without a predominant pattern; II. & III. An increase of systolic pressure which was accetuated at 0600 H. group IV. Showed the lowest tensional levels without special characteristics. Through these data, it seems that the central nervous system loses control upon daily regulation of blood pressure in preeclamptic women.
已有报道称妊娠高血压患者的血压日节律存在改变，尽管并不一致。因此，我们评估了正常妊娠女性（n = 100）和妊娠相关高血压女性（n = 111）的血压日节律。为了确定高血压可能的病因，根据美国妇产科医师学会的分类对患者进行了细分。（第一组：子痫前期 - 子痫；第二组：慢性高血压；第三组：慢性高血压合并子痫前期；第四组：晚孕期高血压）。使用血压计并由不同观察者进行血压定量测量。正常妊娠者上午收缩压和舒张压均有较高升高，在12:00达到峰值，而24:00时记录到的水平非常低。总体而言，高血压组呈现节律丧失；而按组来看：第一组无节律且无主导模式；第二组和第三组收缩压升高，在06:00时加剧。第四组血压水平最低，无特殊特征。通过这些数据，似乎子痫前期女性的中枢神经系统在血压的日常调节上失去了控制。
