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正常妊娠和异常妊娠时血压的变异性

Variability of blood pressure in normal and abnormal pregnancy.

作者信息

Redman C W, Beilin L J, Bonnar J

出版信息

Perspect Nephrol Hypertens. 1976;5:53-60.

PMID:1034277
Abstract

Using an automatic indirect method of measurement, diurnal blood pressure patterns have been studied in normal and hypertensive pregnancies. In the last trimester, normotensive and hypertensive pregnant subjects show small but significant increases of blood pressure that develop especially during the evening and night. This change is more clear-cut for the systolic than the diastolic pressure. The tendency to a relatively greater increased pressure at night is exaggerated in preeclampsia. This fact explains earlier observations of a dimunution of the nocturnal fall of blood pressure in preeclampsia. In very severe preeclampsia, the nocturnal increase of blood pressure may be so exaggerated as to reverse the normal diurnal blood pressure pattern. These changes have been documented sequentially, and their implications are discussed briefly.

摘要

采用自动间接测量方法,对正常妊娠和高血压妊娠的血压昼夜模式进行了研究。在妊娠晚期,血压正常和高血压的孕妇血压有小幅但显著的升高,尤其是在傍晚和夜间。这种变化在收缩压上比舒张压上更为明显。夜间血压相对升高的趋势在子痫前期更为明显。这一事实解释了早期观察到的子痫前期夜间血压下降幅度减小的现象。在非常严重的子痫前期,夜间血压升高可能会非常明显,以至于逆转正常的血压昼夜模式。这些变化已被依次记录,并对其影响进行了简要讨论。

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Variability of blood pressure in normal and abnormal pregnancy.正常妊娠和异常妊娠时血压的变异性
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引用本文的文献

1
Circadian rhythm of maternal blood pressure and fetal growth.母体血压与胎儿生长的昼夜节律。
Biomed Pharmacother. 2005 Oct;59 Suppl 1(Suppl 1):S86-91. doi: 10.1016/s0753-3322(05)80015-0.
2
Hypertension in pregnancy. Pathophysiology and management.妊娠期高血压。病理生理学与管理
Drugs. 1984 Aug;28(2):170-88. doi: 10.2165/00003495-198428020-00005.
3
A study of the disposition of alpha-methyldopa in newborn infants following its administration to the mother for the treatment of hypertension during pregnancy.一项关于母亲在孕期因治疗高血压而服用α-甲基多巴后,新生儿体内该药物处置情况的研究。
Br J Clin Pharmacol. 1979 Nov;8(5):433-40. doi: 10.1111/j.1365-2125.1979.tb01022.x.