GOAnno：基于多重比对的基因本体论注释
GOAnno: GO annotation based on multiple alignment.
作者信息
Chalmel F, Lardenois A, Thompson J D, Muller J, Sahel J-A, Léveillard T, Poch O
机构信息
Laboratoire de Biologie et Génomique Structurales, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP BP 163, Illkirch , France.
出版信息
Bioinformatics. 2005 May 1;21(9):2095-6. doi: 10.1093/bioinformatics/bti252. Epub 2005 Jan 12.
UNLABELLED
GOAnno is a web tool that automatically annotates proteins according to the Gene Ontology (GO) using evolutionary information available in hierarchized multiple alignments. GO terms present in the aligned functional subfamily can be cross-validated and propagated to obtain highly reliable predicted GO annotation based on the GOAnno algorithm.
AVAILABILITY
The web tool and a reduced version for local installation are freely available at http://igbmc.u-strasbg.fr/GOAnno/GOAnno.html
SUPPLEMENTARY INFORMATION
The website supplies a detailed explanation and illustration of the algorithm at http://igbmc.u-strasbg.fr/GOAnno/GOAnnoHelp.html.
未标注
GOAnno是一种网络工具，它利用分层多序列比对中可用的进化信息，根据基因本体论（GO）自动注释蛋白质。比对的功能亚家族中存在的GO术语可以进行交叉验证并传播，以基于GOAnno算法获得高度可靠的预测GO注释。
可用性
该网络工具和用于本地安装的简化版本可从http://igbmc.u-strasbg.fr/GOAnno/GOAnno.html免费获取。
补充信息
该网站在http://igbmc.u-strasbg.fr/GOAnno/GOAnnoHelp.html提供了该算法的详细解释和说明。
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