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来自临床标本和鼻腔定植的mecA阳性金黄色葡萄球菌分离株的抗生素耐药模式

Antibiotic resistance patterns of mecA-positive Staphylococcus aureus isolates from clinical specimens and nasal carriage.

作者信息

Al-Zu'bi Enas, Bdour Salwa, Shehabi Asem A

机构信息

Department of Biological Sciences, Faculty of Science, University of Jordan, Amman, Jordan.

出版信息

Microb Drug Resist. 2004 Winter;10(4):321-4. doi: 10.1089/mdr.2004.10.321.

Abstract

The present study demonstrates that the nasal carriage rate of Staphylococcus aureus was 40% in Jordanian healthy young adult population, and 19% of nasal S. aureus and 57% of clinical isolates over the same period were resistant to oxacillin (MRSA), respectively. The mecA gene was detected in all MRSA isolates in both groups. Most of MRSA isolates were multiresistant to three antibiotic classes (beta-lactams, aminoglycosides, macrolides-lincosamides). This result suggests a serious problem may be encountered in treatment of staphylococcal infections in Jordan.

摘要

本研究表明,在约旦健康年轻成年人群中,金黄色葡萄球菌的鼻腔携带率为40%,同期鼻腔分离的金黄色葡萄球菌中有19%以及临床分离株中有57%对苯唑西林耐药(耐甲氧西林金黄色葡萄球菌)。在两组的所有耐甲氧西林金黄色葡萄球菌分离株中均检测到mecA基因。大多数耐甲氧西林金黄色葡萄球菌分离株对三类抗生素(β-内酰胺类、氨基糖苷类、大环内酯类-林可酰胺类)多重耐药。这一结果表明,约旦在治疗葡萄球菌感染时可能会遇到严重问题。

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