Omidian Hossein, Rocca Jose G, Park Kinam
Kos Pharmaceuticals, Inc., Solid Dose Research and Development Hollywood, FL 33020, USA.
J Control Release. 2005 Jan 20;102(1):3-12. doi: 10.1016/j.jconrel.2004.09.028.
Superporous hydrogels (SPHs) are different from superabsorbent polymers (SAPs) in that SPHs swell fast, within minutes, to the equilibrium swollen state regardless of their size. The fast swelling property is based on water absorption through open porous structure by capillary force. The poor mechanical strength of SPHs was overcome by developing the second-generation SPH composites (SPHCs) and the third-generation SPH hybrids (SPHHs). This review examines the differences between SAPs and SPHs and describes three different generations of SPHs.
高吸水性水凝胶(SPHs)与高吸水性聚合物(SAPs)不同,在于SPHs能在几分钟内迅速膨胀至平衡溶胀状态,而与它们的尺寸无关。这种快速溶胀特性基于通过开放多孔结构利用毛细管力吸水。通过开发第二代高吸水性水凝胶复合材料(SPHCs)和第三代高吸水性水凝胶杂化材料(SPHHs),克服了SPHs机械强度差的问题。本文综述了SAPs和SPHs之间的差异,并描述了三代不同的SPHs。