Jounieaux V, Demey I, Levi-Valensi P
Service de Pneumologie, CHU, Hôpital Sud, Amiens.
Rev Mal Respir. 1992;9(2):205-7.
The authors report the case of a patient with chronic obstructive pulmonary disease (COPD) whose renal function depends on the ventilatory pattern. The data appeared in opposition with the standard physiopathological notions with an improvement of renal function during mechanical ventilatory assistance and a degradation while spontaneous breathing. The authors suggest an original hypothesis based upon the increase of oxygen cost of breathing (OCB) with a redistribution of the intravascular blood flow to the diaphragm.
作者报告了一例慢性阻塞性肺疾病（COPD）患者的病例，该患者的肾功能取决于通气模式。数据似乎与标准的生理病理概念相悖，在机械通气辅助期间肾功能改善，而自主呼吸时肾功能恶化。作者基于呼吸氧耗（OCB）增加以及血管内血流重新分布至膈肌提出了一个全新的假说。
