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西北边境省布内尔地区丙型肝炎的发病率

Frequency of hepatitis "C" in Buner, NWFP.

作者信息

Muhammad Noor, Jan M Ayub

机构信息

Department of Medicine, District Headquarter Hospital, Daggar, Buner.

出版信息

J Coll Physicians Surg Pak. 2005 Jan;15(1):11-4.

PMID:15670516
Abstract

OBJECTIVE

To assess the frequency of hepatitis C in District Buner.

DESIGN

Descriptive study.

PLACE AND DURATION OF STUDY

This study was conducted on outdoor patients in Medical OPD of District Headquarter (DHQ) Hospital, Daggar from January 1998 to December 2002.

PATIENTS AND METHODS

A total of 16,400 patients of age between (15-70 years), who attended the outpatients department of Medical Unit at DHQ, Daggar with non-specific symptoms of dyspepsia, heart burn, bloating, generalized body aches and pain in right hypochondrium were screened for anti-HCV anti-bodies by 3rd generation ELISA. PCR and abdominal ultrasound was also done. Standard treatment was also given. Risk factors were evaluated. Population of district was regionwise divided into sectors A-D and then into subsectors.

RESULTS

Out of 16,400 patients, 751 were found positive for anti-HCV antibodies (4.57%). The mean age of the patients was 37 years. The youngest was 15 years while the oldest was 65 years. The frequency of hepatitis C was higher among the male, 409/751 (54.46%) as compared to female, 342/751(45.53%). Hundred percent (751/751) had history of injections, 52/751 (6.92 %) had major surgery, 8/751 (1.06%) had blood transfusion, 73/751 (9.72%) had dental procedure, 3/751 (0.39%) had tattooing and 332/751 (44.20%) had shaving by community barbers. The highest prevalence of hepatitis C was found in sector A1(9.7%) and the lowest in sector D3(0.5%).

CONCLUSION

Hepatitis C is a common health problem in District Buner, and needs proper attention to alleviate the suffering of the people. It is essential to assess the magnitude of the problem, which will help us in understanding the dynamic of its transmission for control and prevention.

摘要

目的

评估布内尔地区丙型肝炎的感染率。

设计

描述性研究。

研究地点及时间

本研究于1998年1月至2002年12月在达格加区总部医院(DHQ)医疗门诊的门诊患者中进行。

患者及方法

共有16400名年龄在15至70岁之间、因消化不良、烧心、腹胀、全身疼痛及右季肋部疼痛等非特异性症状前往达格加区总部医院医疗科门诊就诊的患者,通过第三代酶联免疫吸附测定法(ELISA)筛查抗丙型肝炎病毒(HCV)抗体。同时进行了聚合酶链反应(PCR)和腹部超声检查,并给予了标准治疗。对危险因素进行了评估。该地区人口按区域分为A - D四个区,然后再分为小区。

结果

在16400名患者中,751人抗HCV抗体检测呈阳性(4.57%)。患者的平均年龄为37岁。最年轻的15岁,最年长的65岁。丙型肝炎在男性中的感染率较高,为409/751(54.46%),而女性为342/751(45.53%)。100%(751/751)的患者有注射史,52/751(6.92%)有大手术史,8/751(1.06%)有输血史,73/751(9.72%)有牙科治疗史,3/751(0.39%)有纹身史,332/751(44.20%)有社区理发师剃须史。丙型肝炎感染率最高的是A1区(9.7%),最低的是D3区(0.5%)。

结论

丙型肝炎是布内尔地区常见的健康问题,需要给予适当关注以减轻民众的痛苦。评估该问题的严重程度至关重要,这将有助于我们了解其传播动态以便进行控制和预防。

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