2%利多卡因中肾上腺素制剂的过敏反应：两例报告
Allergic reaction to epinephrine preparation in 2% lidocaine: two case reports.
作者信息
Kohase Hikaru, Umino Masahiro
机构信息
Section of Anesthesiology and Clinical Physiology, Department of Oral Restitution, Division of Oral Sciences, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.
出版信息
Anesth Prog. 2004;51(4):134-7.
We report 2 cases of hypersensitivity to an epinephrine preparation in local anesthetics which were found by skin tests for local anesthetics. Both patients had uncomfortable episodes to local anesthetics at dental treatment. In both cases, the skin tests showed positive reactions to 2% lidocaine with 1:80,000 epinephrine. Furthermore drug lymphocyte stimulation test revealed positive reaction to epinephrine hydrochloride, epinephrine bitartrate in case 1, whereas in case 2, the drug lymphocyte stimulation test showed positive response to epinephrine bitartrate. Attention should be paid to exogenous epinephrine preparations that have the potential to induce hypersensitivity during dental treatment.
我们报告了2例在局部麻醉剂中对肾上腺素制剂过敏的病例，这些病例是通过局部麻醉剂皮肤试验发现的。两名患者在牙科治疗时对局部麻醉剂均有不适反应。在这两例病例中，皮肤试验显示对含1:80,000肾上腺素的2%利多卡因呈阳性反应。此外，药物淋巴细胞刺激试验显示，病例1对盐酸肾上腺素、重酒石酸肾上腺素呈阳性反应，而病例2的药物淋巴细胞刺激试验显示对重酒石酸肾上腺素呈阳性反应。在牙科治疗期间，应注意有可能诱发过敏反应的外源性肾上腺素制剂。
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