生殖支原体：一种在西非性工作者中常与宫颈炎相关的微生物。
Mycoplasma genitalium: an organism commonly associated with cervicitis among west African sex workers.
作者信息
Pépin J, Labbé A-C, Khonde N, Deslandes S, Alary M, Dzokoto A, Asamoah-Adu C, Méda H, Frost E
机构信息
Department of Microbiology and Infectious Diseases, University of Sherbrooke, Sherbrooke, Canada.
出版信息
Sex Transm Infect. 2005 Feb;81(1):67-72. doi: 10.1136/sti.2003.009100.
OBJECTIVES
To identify the contribution of Mycoplasma genitalium to the aetiology of cervicitis in sub-Saharan Africa and its relative importance in the overall burden of sexually transmitted infections among female sex workers (FSW).
METHODS
The study population consisted of FSW recruited in Ghana and Benin during the initial visit of a randomised controlled trial. A questionnaire was administered, a pelvic examination carried out, and cervical samples obtained for detection of M genitalium, Neisseria gonorrhoeae, Chlamydia trachomatis, and Trichomonas vaginalis. Clinical signs potentially indicating cervicitis were cervical discharge, pus on the cervical swab, bleeding after sampling, and inflammatory cervix.
RESULTS
Among 826 FSW, 26.3% were infected with M genitalium. N gonorrhoeae was strongly and independently associated with each of the four signs of cervicitis (adjusted odds ratios (AOR): 4.1 to 6.0). The AOR for C trachomatis were intermediate (1.3-4.1) and the AOR for M genitalium were lower (between 1.6 and 1.8) but statistically significant (p< or =0.05) for each sign.
CONCLUSIONS
M genitalium is weakly associated with signs of cervicitis in west African FSW but is highly prevalent.
目的
确定生殖支原体在撒哈拉以南非洲宫颈炎病因学中的作用及其在女性性工作者（FSW）性传播感染总体负担中的相对重要性。
方法
研究人群包括在加纳和贝宁一项随机对照试验初次访视期间招募的FSW。进行问卷调查、盆腔检查，并采集宫颈样本以检测生殖支原体、淋病奈瑟菌、沙眼衣原体和阴道毛滴虫。潜在提示宫颈炎的临床体征为宫颈分泌物、宫颈拭子上有脓液、采样后出血以及宫颈炎症。
结果
在826名FSW中，26.3%感染了生殖支原体。淋病奈瑟菌与宫颈炎的四种体征均密切且独立相关（校正比值比（AOR）：4.1至6.0）。沙眼衣原体的AOR为中等（1.3 - 4.1），生殖支原体的AOR较低（1.6至1.8之间），但每种体征的AOR均具有统计学意义（p≤0.05）。
结论
生殖支原体与西非FSW的宫颈炎体征关联较弱，但感染率很高。
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