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通过双腔气管导管进行吸痰有助于防止肺泡塌陷并维持通气。

Suctioning through a double-lumen endotracheal tube helps to prevent alveolar collapse and to preserve ventilation.

作者信息

Reissmann Hajo, Böhm Stephan H, Suárez-Sipmann Fernando, Tusman Gerardo, Buschmann Claas, Maisch Stefan, Pesch Tanja, Thamm Oliver, Plümers Christoph, Schulte am Esch Jochen, Hedenstierna Göran

机构信息

Department of Anesthesiology, Universitätsklinikum Hamburg-Eppendorf, Germany.

出版信息

Intensive Care Med. 2005 Mar;31(3):431-40. doi: 10.1007/s00134-004-2537-5. Epub 2005 Feb 3.

Abstract

OBJECTIVE

Endotracheal suctioning can cause alveolar collapse and impede ventilation. One reason is the gas flow through a single-lumen endotracheal tube (ETT) provoking a gradient between airway opening and tracheal (P(tr)) pressures. Separately extending the patient tubing limbs of a suitable ventilator into the trachea via a double-lumen ETT should maintain P(tr). Can this technique reduce the side effects?

DESIGN AND SETTING

Bench and animal studies in a university hospital laboratory.

INTERVENTIONS

A lung model was ventilated via single and double-lumen ETTs. Closed-system suctioning was applied with catheters introduced into the single-lumen ETT or the expiratory lumen of the double-lumen ETT via swivel adapter. Seven anesthetized pigs (lungs lavaged) underwent three runs of ventilation and suctioning through (a, b) an 8.0-mm ID single-lumen ETT, (c) a double-lumen ETT (41Ch outer diameter, OD). In (a) the single-lumen ETT was disconnected for suctioning, in (b) and (c) ventilator mode was set to continuous positive airway pressure mode, and the ETTs remained connected.

MEASUREMENTS AND RESULTS

Bench: Suction through single-lumen ETTs impaired ventilation and led to strongly negative P(tr) (common: -10 to -20 mbar); the double-lumen ETT technique maintained ventilation and pressures.

ANIMALS

Lung gas content (computed tomography, n=4) and arterial oxygen partial pressure, initially 1462+/-65 ml/532+/-76 mmHg, were significantly reduced by suctioning through single-lumen ETT: to 302+/-79 ml/62+/-6 mmHg with disconnection and to 851+/-211 ml/158+/-107 mmHg with closed suction. With double-lumen ETT they remained at 1377+/-95 ml/521+/-56 mmHg.

CONCLUSIONS

The double-lumen ETT technique minimizes side effects of suctioning by maintaining P(tr).

摘要

目的

气管内吸痰可导致肺泡塌陷并阻碍通气。原因之一是通过单腔气管内导管(ETT)的气流会在气道开口与气管(P(tr))压力之间形成梯度。通过双腔ETT将合适呼吸机的患者管路分支分别延伸至气管内应能维持P(tr)。该技术能否减少副作用?

设计与场所

大学医院实验室的实验台和动物研究。

干预措施

通过单腔和双腔ETT对肺模型进行通气。使用导管经旋转接头插入单腔ETT或双腔ETT的呼气腔进行封闭系统吸痰。七只麻醉猪(肺已灌洗)通过(a、b)外径8.0毫米的单腔ETT、(c)双腔ETT(外径41Ch)进行三轮通气和吸痰。在(a)中,断开单腔ETT进行吸痰;在(b)和(c)中,将呼吸机模式设置为持续气道正压模式,ETT保持连接。

测量与结果

实验台:通过单腔ETT吸痰会损害通气并导致P(tr)显著为负(常见:-10至-20毫巴);双腔ETT技术可维持通气和压力。

动物

通过单腔ETT吸痰会使肺气体含量(计算机断层扫描,n = 4)和动脉血氧分压(初始为1462±65毫升/532±76毫米汞柱)显著降低:断开连接时降至302±79毫升/62±6毫米汞柱,封闭吸痰时降至851±211毫升/158±107毫米汞柱。使用双腔ETT时,它们保持在1377±95毫升/521±56毫米汞柱。

结论

双腔ETT技术通过维持P(tr)将吸痰的副作用降至最低。

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