预防慢性阻塞性肺疾病急性加重的干预措施。

Interventions to prevent chronic obstructive pulmonary disease exacerbations.

作者信息

Niewoehner Dennis E

机构信息

Pulmonary Section, Veterans Affairs Medical Center, and Department of Medicine, University of Minnesota, Minneapolis, Minnesota 55417, USA.

出版信息

Am J Med. 2004 Dec 20;117 Suppl 12A(12):41S-48S. doi: 10.1016/j.amjmed.2004.10.021.

DOI:10.1016/j.amjmed.2004.10.021

PMID:15693642

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7185512/

Abstract

Exacerbations of chronic obstructive pulmonary disease (COPD) have a profound effect on the patient's health status and decline in lung function; they also impose a significant burden on healthcare resource utilization. Prevention and treatment of exacerbations is listed by the Global Initiative for Chronic Obstructive Lung Disease (GOLD) as among the major objectives of COPD management, and it is therefore an important outcome measure when studying any new agent. This article discusses pharmacologic therapy and other measures for preventing exacerbations and hospitalizations due to exacerbations of COPD.

摘要

慢性阻塞性肺疾病（COPD）急性加重对患者的健康状况和肺功能下降有深远影响；它们还对医疗资源的利用造成重大负担。慢性阻塞性肺疾病全球倡议（GOLD）将急性加重的预防和治疗列为COPD管理的主要目标之一，因此在研究任何新药时，这是一项重要的结局指标。本文讨论了预防COPD急性加重及因急性加重导致住院的药物治疗和其他措施。