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[献血者中乙型和丙型肝炎病毒、人类免疫缺陷病毒及梅毒的血清流行率]

[Seroprevalence of hepatitis B and C virus, human immunodeficiency virus and syphilis in the blood donors].

作者信息

Mutlu Birsen, Meriç Meliha, Willke Ayşe

机构信息

Kocaeli Universitesi Tip Fakültesi, Klinik Bakteriyoloji ve infeksiyon Hastaliklari Anabilim Dali, Kocaeli.

出版信息

Mikrobiyol Bul. 2004 Oct;38(4):445-8.

Abstract

Transfusion-transmitted infections are the most commonly encountered complications in transfusion practice. Serological markers for hepatitis B virus (HBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV) and Treponema pallidum were screened in blood banks routinely. These tests are obligatory for transfusion safety and may give an idea about the seropositivity rates of a specific region. In this study, the results of 29,049 volunteer blood donors who were admitted to Blood Center of Kocaeli University Hospital between January 1999 to January 2004, have been retrospectively evaluated. HBsAg, anti-HCV and anti-HIV-1/2 were screened by microparticle enzyme immunoassay (MEIA), and syphilis antibodies were screened by rapid plasma reagin (RPR) test in the Blood Center Laboratory. The seropositivity rates for HBsAg, anti-HCV and RPR were found as 2.3%, 0.37% and 0.02%, respectively. Eight donors were found seropositive for anti-HIV-1/2, but they were all accepted as false positive results, since the western blot confirmation tests were all negative.

摘要

输血传播感染是输血实践中最常见的并发症。血库常规筛查乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)、人类免疫缺陷病毒(HIV)和梅毒螺旋体的血清学标志物。这些检测对于输血安全是必不可少的,并且可以了解特定地区的血清阳性率。在本研究中,对1999年1月至2004年1月期间入住科贾埃利大学医院血库的29049名志愿献血者的结果进行了回顾性评估。在血库实验室中,采用微粒酶免疫分析(MEIA)筛查HBsAg、抗-HCV和抗-HIV-1/2,采用快速血浆反应素(RPR)试验筛查梅毒抗体。发现HBsAg、抗-HCV和RPR的血清阳性率分别为2.3%、0.37%和0.02%。8名献血者抗-HIV-1/2血清学检测呈阳性,但由于免疫印迹确认试验均为阴性,他们均被视为假阳性结果。

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