Enria D A M, Levis S C
Instituto Nacional de Enfermedades Virales Humanas Dr. J. Maiztegui, Monteagudo 2510, 2700 Pergamino, Argentina.
Rev Sci Tech. 2004 Aug;23(2):595-611.
Hantaviruses are rodent-borne agents belonging to the Bunyaviridae family. These viruses, which are found throughout Europe, Asia and the Americas, are maintained by different species of rodents, in which they produce chronic, inapparent infections. Humans become infected through contact with urine, saliva or faeces from infected rodents, mainly via the aerosol route. In humans, clinical disease occurs in the form of two major syndromes: haemorrhagic fever with renal syndrome (HFRS) or hantavirus pulmonary syndrome (HPS). Haemorrhagic fever with renal syndrome mainly occurs in Europe and Asia and HPS has only ever been reported in the Americas. Person-to-person transmission of hantaviruses, although uncommon, was described during an outbreak of HPS in southern Argentina. Most epidemics of HFRS and HPS occur in areas with large populations of rodents that have a relatively high prevalence of infection.
汉坦病毒是属于布尼亚病毒科的啮齿动物传播媒介。这些病毒分布于欧洲、亚洲和美洲,由不同种类的啮齿动物传播,在这些动物中会引发慢性、隐性感染。人类主要通过气溶胶途径接触受感染啮齿动物的尿液、唾液或粪便而被感染。在人类中,临床疾病以两种主要综合征的形式出现:肾综合征出血热(HFRS)或汉坦病毒肺综合征(HPS)。肾综合征出血热主要发生在欧洲和亚洲,而汉坦病毒肺综合征仅在美洲有过报道。在阿根廷南部的一次汉坦病毒肺综合征疫情期间,曾描述过汉坦病毒在人与人之间的传播,尽管这种情况并不常见。大多数肾综合征出血热和汉坦病毒肺综合征疫情发生在啮齿动物数量众多且感染率相对较高的地区。