来自乌桕巴豆的龙血对皮肤癣菌的体外抗真菌活性。
In vitro antifungal activity of dragon's blood from Croton urucurana against dermatophytes.
作者信息
Gurgel Luilma A, Sidrim J J C, Martins Domingos T, Cechinel Filho V, Rao Vietla S
机构信息
Departamento de Fisiologia e Farmacologia, FM, Universidade Federal do Ceará, Rua Cel Nunes de Melo, 1127, Porangabussu, Caixa Postal-3157, 60430-270 Fortaleza, CE, Brazil.
出版信息
J Ethnopharmacol. 2005 Feb 28;97(2):409-12. doi: 10.1016/j.jep.2004.11.033. Epub 2005 Jan 16.
Based on ethnobotanical approach, the dragon's blood collected from Croton urucurana Baill. bark (Euphorbiaceae) was tested for antifungal activity against five dermatophytes by paper disk diffusion method. The minimal inhibitory concentration (MIC) showing no visible fungal growth was also determined, using tube dilution technique. The test dermatophytes were Tricophyton tonsurans, Trichophyton mentagrophytes, Trichophyton rubrum, Microsporum canis and Epidermophyton floccossum. The dragon's blood (0.175-3.0 mg/ml) exhibited an inhibition zone range of 7.6-26.9 mm against all the tested fungi with minimal inhibitory concentrations of 1.25-2.5 mg/ml.
基于民族植物学方法，采用纸片扩散法对从巴豆属植物乌鲁库拉纳巴豆（大戟科）树皮中采集的龙血进行了针对五种皮肤癣菌的抗真菌活性测试。还使用试管稀释技术测定了无可见真菌生长的最低抑菌浓度（MIC）。受试皮肤癣菌为断发毛癣菌、须癣毛癣菌、红色毛癣菌、犬小孢子菌和絮状表皮癣菌。龙血（0.175 - 3.0毫克/毫升）对所有受试真菌的抑菌圈范围为7.6 - 26.9毫米，最低抑菌浓度为1.25 - 2.5毫克/毫升。
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