Langley R G B, Krueger G G, Griffiths C E M
Division of Dermatology, Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada B3H 1V6.
Ann Rheum Dis. 2005 Mar;64 Suppl 2(Suppl 2):ii18-23; discussion ii24-5. doi: 10.1136/ard.2004.033217.
Psoriasis is a common chronic, recurrent, immune mediated disease of the skin and joints. It can have a significant negative impact on the physical, emotional, and, psychosocial wellbeing of affected patients. Psoriasis is found worldwide but the prevalence varies among different ethnic groups. It has a strong genetic component but environmental factors such as infections can play an important role in the presentation of disease. There are several clinical cutaneous manifestations of psoriasis but most commonly the disease presents as chronic, symmetrical, erythematous, scaling papules and plaques. The epidemiology, clinical features, and impact on quality of life of psoriasis are reviewed.
银屑病是一种常见的慢性、复发性、免疫介导的皮肤和关节疾病。它会对受影响患者的身体、情绪及社会心理健康产生重大负面影响。银屑病在全球范围内均有发现,但不同种族群体中的患病率有所不同。它具有很强的遗传成分,但诸如感染等环境因素在疾病表现中也可发挥重要作用。银屑病有多种临床皮肤表现,但最常见的是表现为慢性、对称性、红斑性、鳞屑性丘疹和斑块。本文综述了银屑病的流行病学、临床特征及其对生活质量的影响。