Wszolek Z K, Herkes G K, Lagerlund T D, Kokmen E
Department of Neurology, Mayo Clinic, Rochester, MN 55905.
J Geriatr Psychiatry Neurol. 1992 Jan-Mar;5(1):22-30. doi: 10.1177/002383099200500104.
Fourteen patients who had cognitive dysfunction were studied with quantitative electroencephalography (EEG), single-photon emission computed tomography (SPECT), and several tests of intellectual and memory function, including the Wechsler Adult Intelligence Scale (WAIS), the Auditory Verbal Learning Test, and the Short Test of Mental Status, to determine whether EEG background frequency content correlates with degree of dementia and with regional uptake of radioisotope on SPECT. The factors from spectral analysis that correlated best with psychometric data were mean frequency in the 1.5- to 20-Hz range and percentage power in the 13- to 20-Hz band (positive correlation) or the 1.5- to 8-Hz band (negative correlation). The WAIS subtest scores that correlated most with the EEG data were performance IQ and perceptual organization. Correlations between percentage power and amplitude ratio in the EEG frequency bands and regional SPECT counts were found, but most were not statistically significant.
对14名患有认知功能障碍的患者进行了定量脑电图（EEG）、单光子发射计算机断层扫描（SPECT）以及多项智力和记忆功能测试，包括韦氏成人智力量表（WAIS）、听觉言语学习测试和简易精神状态检查，以确定EEG背景频率成分是否与痴呆程度以及SPECT上放射性同位素的区域摄取相关。频谱分析中与心理测量数据相关性最佳的因素是1.5至20赫兹范围内的平均频率以及13至20赫兹频段的功率百分比（正相关）或1.5至8赫兹频段的功率百分比（负相关）。与EEG数据相关性最高的WAIS子测试分数是操作智商和知觉组织。发现EEG频段的功率百分比与振幅比和区域SPECT计数之间存在相关性，但大多数无统计学意义。
