Staurenghi Giovanni, Viola Francesco, Mainster Martin A, Graham Raymond D, Harrington Peter G
University Eye Clinic, University of Brescia, Brescia, Italy.
Arch Ophthalmol. 2005 Feb;123(2):244-52. doi: 10.1001/archopht.123.2.244.
To perform fluorescein and indocyanine green angiography for large or peripheral chorioretinal structures using a contact lens system that provides a 5-fold increase in the field of view of a confocal scanning laser ophthalmoscope (SLO).
Separate handheld contact and noncontact ophthalmoscopic lenses were manually aligned with the optical axis of a confocal SLO to demonstrate the feasibility of wide-field SLO angiography. An integrated, wide-field contact lens system was then designed and constructed to increase the SLO's 10 degrees , 20 degrees , and 30 degrees imaging fields to 50 degrees , 100 degrees , and 150 degrees , respectively.
Simultaneous fluorescein and indocyanine green angiography was performed with the integrated, wide-field contact lens system for more than 50 patients with disorders that affect their peripheral retina and choroid. Retinal and choroidal abnormalities, including neovascularization and capillary nonperfusion, are easily detected and documented well beyond the range of conventional fundus cameras and SLOs. Peripheral retinal and choroidal hemodynamics can be readily observed and recorded.
A confocal SLO has adequate resolution for clinically useful reflectance and angiographic imaging even when its field size is increased 5-fold by a wide-field contact lens system. Dynamic and static wide-field angiography can be performed without the limitations of manual or computer-automated photomontages. Peripheral retinal conditions can be studied and recorded to confirm observations from indirect ophthalmoscopy and to facilitate retinal photocoagulation and vitreoretinal surgery.
使用一种可使共焦扫描激光检眼镜(SLO)视野增大5倍的隐形眼镜系统,对大的或周边脉络膜视网膜结构进行荧光素和吲哚菁绿血管造影。
将单独的手持式接触式和非接触式检眼镜镜片手动与共焦SLO的光轴对齐,以证明宽视野SLO血管造影的可行性。然后设计并构建了一个集成的宽视野隐形眼镜系统,将SLO的10度、200度和30度成像视野分别增加到50度、100度和150度。
使用集成的宽视野隐形眼镜系统对50多名患有影响周边视网膜和脉络膜疾病的患者进行了同步荧光素和吲哚菁绿血管造影。视网膜和脉络膜异常,包括新生血管形成和毛细血管无灌注,在常规眼底照相机和SLO的范围之外很容易被检测到并得到很好的记录。周边视网膜和脉络膜血流动力学可以很容易地被观察和记录。
即使其视野大小通过宽视野隐形眼镜系统增加了5倍,共焦SLO对于临床有用的反射率和血管造影成像仍具有足够的分辨率。可以进行动态和静态宽视野血管造影,而不受手动或计算机自动拼接的限制。可以研究和记录周边视网膜状况,以确认间接检眼镜检查的观察结果,并便于视网膜光凝和玻璃体视网膜手术。