Ellis D
Nephrology Division, Children's Hospital of Pittsburgh, PA 15213.
Pediatr Nephrol. 1992 Mar;6(2):131-4. doi: 10.1007/BF00866291.
This paper describes a healthy 13-year-old girl presenting with acute flank pain and anuria due to renal vein thrombosis. A similar spontaneous and unexplained thrombosis resulted in the loss of the contralateral kidney 1 year earlier. Urgent surgical thrombectomy and anticoagulation resulted in moderate recovery of renal function. Predisposition to venous thrombosis in this child was secondary to a marked familial deficiency of circulating antithrombin-III. An early diagnosis of this condition is essential for the formulation of preventive measures and may lead to specific therapeutic intervention at the onset of acute thrombotic complications.
本文描述了一名13岁健康女孩，因肾静脉血栓形成出现急性胁腹痛和无尿。1年前，类似的自发性不明原因血栓形成导致对侧肾脏丧失。紧急手术取栓和抗凝治疗使肾功能得到中度恢复。该患儿静脉血栓形成的易患因素继发于循环抗凝血酶III明显的家族性缺乏。对这种情况进行早期诊断对于制定预防措施至关重要，并且可能在急性血栓并发症发作时进行特异性治疗干预。
