Atmar R L, Englund J A, Hammill H
Department of Microbiology and Immunology, Baylor College of Medicine, Houston, Texas 77030.
Clin Infect Dis. 1992 Jan;14(1):217-26. doi: 10.1093/clinids/14.1.217.
Twelve pregnant women and one woman who had just given birth were hospitalized with measles in Houston between 1988 and 1990. The most common and serious maternal complication was pneumonitis (seven patients). Other maternal complications included hepatitis (seven patients), premature labor (four patients), spontaneous abortion (one patient), and death (one patient). For four of 13 patients, all of whom had severe measles and pneumonitis due to measles virus, an adverse fetal outcome such as abortion or prematurity was associated with their conditions. Historical accounts describing maternal sequelae of measles have suggested more severe disease in pregnant women, although this observation has not always been confirmed by more recent reports in developed countries. The clinical course in our patients suggests that measles during pregnancy may be associated with serious complications.
1988年至1990年间，休斯顿有12名孕妇和1名刚分娩的妇女因麻疹住院。最常见且严重的孕产妇并发症是肺炎（7例）。其他孕产妇并发症包括肝炎（7例）、早产（4例）、自然流产（1例）和死亡（1例）。13名患者中有4名，均因麻疹病毒感染而患重症麻疹和肺炎，其病情与不良胎儿结局如流产或早产有关。描述麻疹孕产妇后遗症的历史记载表明，孕妇患麻疹病情更严重，尽管发达国家的最新报告并非总能证实这一观察结果。我们患者的临床病程表明，孕期麻疹可能与严重并发症有关。
