Wen Li-Xiong, Li Zhu-Zhu, Zou Hai-Kui, Liu An-Qi, Chen Jian-Feng
Key Laboratory for Nanomaterials, Ministry of Education, Research Centre of the Ministry of Education for High Gravity Engineering and Technology, Beijing University of Chemical Technology, Beijing 100029, China.
Pest Manag Sci. 2005 Jun;61(6):583-90. doi: 10.1002/ps.1032.
Porous hollow silica nanoparticles (PHSNs) with a diameter of ca 100 nm and a pore size of ca 4.5 nm were synthesized via a sol-gel route using inorganic calcium carbonate nanoparticles as templates. The synthesized PHSNs were subsequently employed as pesticide carriers to study the controlled release behaviour of avermectin. The avermectin-loaded PHSN (Av-PHSN) samples were characterized by BET, thermogravimetric analysis and IR, showing that the amount of avermectin encapsulated in the PHSN carrier could reach 58.3% w/w by a simple immersion loading method, and that most of the adsorption of avermectin on the Av-PHSN carrier might be physical. Avermectin may be loaded on the external surface, the pore channels in the wall and the inner core of the PHSN carriers, thus leading to a multi-stage sustained-release pattern from the Av-PHSN samples. Increasing pH or temperature intensified the avermectin release.
采用无机碳酸钙纳米粒子作为模板，通过溶胶-凝胶法合成了直径约为100 nm、孔径约为4.5 nm的多孔中空二氧化硅纳米粒子（PHSNs）。随后将合成的PHSNs用作农药载体，研究阿维菌素的控释行为。通过BET、热重分析和红外光谱对负载阿维菌素的PHSN（Av-PHSN）样品进行了表征，结果表明，通过简单的浸泡负载法，PHSN载体中包裹的阿维菌素量可达58.3% w/w，且阿维菌素在Av-PHSN载体上的吸附大多可能是物理吸附。阿维菌素可能负载在PHSN载体的外表面、壁上的孔道和内核中，从而导致Av-PHSN样品呈现多阶段缓释模式。提高pH值或温度会增强阿维菌素的释放。
