高血压与心绞痛之间的关系。
Relationship between hypertension and angina pectoris.
作者信息
Richardson P J, Hill L S
出版信息
Br J Clin Pharmacol. 1979;7 Suppl 2(Suppl 2):249S-253S. doi: 10.1111/j.1365-2125.1979.tb04697.x.
Abstract
1 Many factors are of importance in the relationship between angina pectoris and hypertensive heart disease. Vascular resistance modifies the oxygen supply, whereas the oxygen demand is influenced by the systolic and diastolic BPs, the diastolic filling time and wall tension, the duration of systole and transmural pressure and the sympathetic stimulation to the heart. 2 The treatment of angina pectoris in patients with hypertensive heart disease should aim to reduce myocardial ischaemia, and it is suggested that beta-adrenoceptor antagonists are most suitable, as they reduce BP, heart rate and myocardial contractility and thus oxygen demand.
摘要
- 许多因素在心绞痛与高血压性心脏病的关系中至关重要。血管阻力会改变氧气供应，而氧气需求则受收缩压和舒张压、舒张期充盈时间和壁张力、收缩期持续时间和跨壁压以及心脏交感神经刺激的影响。2. 高血压性心脏病患者心绞痛的治疗应旨在减少心肌缺血，有人认为β肾上腺素能受体拮抗剂最为合适，因为它们可降低血压、心率和心肌收缩力，从而降低氧气需求。
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Relationship between hypertension and angina pectoris.高血压与心绞痛之间的关系。
Br J Clin Pharmacol. 1979;7 Suppl 2(Suppl 2):249S-253S. doi: 10.1111/j.1365-2125.1979.tb04697.x.
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Thirteenth Bowditch lecture. The determinants of myocardial oxygen consumption.第十三届鲍迪奇讲座。心肌耗氧量的决定因素。
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Circulating catecholamine levels in human and experimental hypertension.人类和实验性高血压中的循环儿茶酚胺水平
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