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[年龄对小鼠精原细胞致突变作用敏感性的影响]

[Effect of age on the sensitivity of mouse spermatogonia to mutagenic action].

作者信息

Leonard A, Jacquet P

出版信息

C R Seances Soc Biol Fil. 1978;172(5):1029-32.

PMID:157191
Abstract

Male BALB/c mice were whole body exposed to 0, 100, 200 or 300 R of X-rays or were given an i.p. injection of 5 mg/kg of thio-TEPA at 3 months or at 12 months of age. One hundred days after treatment the testes were examined for the presence of reciprocal translocations induced in spermatogonia and detectable in the dividing spermatocytes. Our results show that ages does not influence the yield of scorable chromosome rearrangements.

摘要

雄性BALB/c小鼠在3个月或12个月龄时，全身接受0、100、200或300伦琴的X射线照射，或者腹腔注射5毫克/千克的塞替派。治疗后100天，检查睾丸中精原细胞诱导产生的、可在分裂中的精母细胞中检测到的相互易位情况。我们的结果表明，年龄不会影响可计分染色体重排的发生率。

相似文献

1
[Effect of age on the sensitivity of mouse spermatogonia to mutagenic action].[年龄对小鼠精原细胞致突变作用敏感性的影响]
C R Seances Soc Biol Fil. 1978;172(5):1029-32.
2
RBE values of d (16) + Be and d (50) + Be neutrons for chromosome rearrangements induced in mouse spermatogonia.用于诱导小鼠精原细胞中染色体重排的氘（16）+铍和氘（50）+铍中子的相对生物效应值。
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[Mutagenic effect of irradiating different species on the sex cells of male mice. VIII. Frequency of development of reciprocal translocations in the spermatogonia of mice subjected to chronic gamma-irradiation].[不同物种辐射对雄性小鼠生殖细胞的诱变作用。VIII. 慢性γ辐射小鼠精原细胞中相互易位的发生频率]
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