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[氚对雄性小鼠生殖细胞的诱变作用。II. 氧化氚和γ辐射诱导的精原干细胞遗传损伤]

[Mutagenic action of tritium on the germ cells of male mice. II. The genetic damages in stem spermatogonia induced by tritium oxide and gamma radiation].

作者信息

Pomerantseva M D, Balonov M I, Ramaĭia L K, Vilkina G A

出版信息

Genetika. 1984 May;20(5):782-7.

PMID:6539724
Abstract

The frequency of reciprocal translocations (RT) induced by single injection of tritiated water (THO) (3.3; 6.3 and 12.6 MBq/g) or by referent 137Cs gamma irradiation was studied. The absorbed doses in testis were: 1; 2 and 4 Gr. The frequency of RT per 100 cells were 0.4; 1.1 and 2.5 after THO administration, and 0,5; 0.9 and 1.2 after single exposure to gamma irradiation, respectively. The RBE of tritium increased from 1 at the dose of 1 Gr to 2, at the dose of 4 Gr.

摘要

研究了单次注射氚水（THO）（3.3；6.3和12.6 MBq/g）或参考性137Csγ射线照射诱导的相互易位（RT）频率。睾丸中的吸收剂量分别为：1；2和4戈瑞。给予THO后每100个细胞的RT频率分别为0.4；1.1和2.5，单次γ射线照射后分别为0.5；0.9和1.2。氚的相对生物效应因子（RBE）从1戈瑞剂量时的1增加到4戈瑞剂量时的2。

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