Piesold J-U, Vent S, Krüger R, Pistner H
Klinik für Mund-, Kiefer- und Gesichtschirurgie/Plastische Operationen, HELIOS-Klinikum Erfurt.
Mund Kiefer Gesichtschir. 2005 May;9(3):143-51. doi: 10.1007/s10006-005-0594-8.
Basal cell carcinomas are the most frequently occurring malignant tumors in the white population. They exhibit a multitude of histological/morphological forms.
All cases of basal cell carcinoma treated at the department for oral and maxillofacial and regional plastic surgery of the HELIOS hospital in Erfurt between 1976 and 2003 were analyzed and partly reexamined in a retrospective study.
A total of 648 patients with 765 basal cell carcinomas were treated. Occurrences in females dominated those in males with a frequency distribution of 1.24:1. The average age was 70.6 years with a significantly larger number of female seniors above 60. In 64% of the cases the basal cell carcinomas were nodular, in 16% infiltrative. Other morphological/histological forms occurred with a frequency of <or=5%. The most frequent localizations were in of the regions of the highest sun exposure such as the nose, midface, and forehead.
If an infiltrative basal cell carcinoma is suspected or insufficient radical primary surgery is presumed, plastic reconstruction should be postponed until free margins can be confirmed histologically. The functional and aesthetic quality of reconstruction was better using pedicled flaps (90%) and primary closure (86%) than using free skin transplants (30-54%). Nevertheless, free skin flaps and epitheses were found to be well accepted by the reexamined patients.
基底细胞癌是白种人群中最常见的恶性肿瘤。它们呈现出多种组织学/形态学形式。
对1976年至2003年间在爱尔福特市HELIOS医院口腔颌面及区域整形手术科室接受治疗的所有基底细胞癌病例进行了分析,并在一项回顾性研究中对部分病例进行了复查。
共治疗了648例患者的765例基底细胞癌。女性发病多于男性,频率分布为1.24:1。平均年龄为70.6岁,60岁以上的女性老年人数量明显更多。64%的病例中基底细胞癌为结节状,16%为浸润性。其他形态学/组织学形式的发生率≤5%。最常见的发病部位是阳光暴露最多的区域,如鼻子、面部中部和前额。
如果怀疑是浸润性基底细胞癌或推测初次根治性手术不彻底,应推迟整形重建,直到组织学检查确认切缘阴性。使用带蒂皮瓣(90%)和一期缝合(86%)进行重建的功能和美学质量优于使用游离皮片移植(30 - 54%)。然而,复查患者对游离皮瓣和假体的接受度良好。