Varda Natasa Marcun, Gregoric Alojz
Department of Pediatrics, Maribor Teaching Hospital, Ljubljanska 5, 2000 Maribor, Slovenia.
Pediatr Nephrol. 2005 Apr;20(4):499-506. doi: 10.1007/s00467-004-1737-0. Epub 2005 Feb 19.
Hypertension during childhood is not rare, with an estimated prevalence of between 1% and 2%, although it is often an underrecognized clinical entity. Elevated blood pressure may be a sign of underlying disease or it may represent early onset of essential hypertension. In recent years the measurement of blood pressure has been emphasized as an important component of the routine pediatric physical examination that enables early detection of children with hypertension. In the evaluation of the child with documented blood pressure elevation, confirmation of truly and persistently elevated blood pressure is of the utmost importance. In addition, a thorough history and a full clinical examination are essential. These are followed by appropriate investigations, which are tailored to the age of the child and to the severity of the blood pressure elevation. Investigations should not only focus on a search for the underlying cause, but also on establishing effects on target organs, complications or additional diseases and on assessment of the total cardiovascular risk to the individual patient. An algorithm, which is a valuable diagnostic tool for the diagnosis and management of the child with hypertension, is presented. All children with confirmed hypertension need long-term follow-up, counseling and treatment. In those cases where an underlying cause of the hypertension is detected, the established diagnosis then determines the specific therapy and management.
儿童期高血压并不罕见,估计患病率在1%至2%之间,尽管它常常是一个未被充分认识的临床实体。血压升高可能是潜在疾病的迹象,也可能代表原发性高血压的早期发病。近年来,血压测量已被强调为常规儿科体格检查的重要组成部分,有助于早期发现高血压儿童。在评估有血压升高记录的儿童时,确认血压真正持续升高至关重要。此外,全面的病史和完整的临床检查必不可少。随后进行适当的检查,这些检查要根据儿童的年龄和血压升高的严重程度进行调整。检查不仅应侧重于寻找潜在病因,还应侧重于确定对靶器官的影响、并发症或其他疾病,并评估个体患者的总体心血管风险。本文介绍了一种算法,它是诊断和管理高血压儿童的有价值的诊断工具。所有确诊高血压的儿童都需要长期随访、咨询和治疗。在那些检测到高血压潜在病因的病例中,既定的诊断随后决定具体的治疗和管理。