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腹膜子宫内膜异位症的三维结构

Three-dimensional architectures of peritoneal endometriosis.

作者信息

Donnez J, Nisolle M, Casanas-Roux F

机构信息

Department of Gynecology, Catholic University of Louvain, Brussels, Belgium.

出版信息

Fertil Steril. 1992 May;57(5):980-3.

PMID:1572492
Abstract

OBJECTIVE

To elucidate some biological characteristics of peritoneal endometriosis.

DESIGN

A recently advanced stereographic computer technology was applied for the investigation of the three-dimensional (3-D) architectures of peritoneal endometriosis.

SETTING

University Hospital of Gynecology.

PATIENTS

Biopsies were taken from 42 women with peritoneal endometriosis. Twenty-six of them were in the luteal phase. Seventeen of them received Zoladex (ICI, Cambridge, United Kingdom) for 12 weeks before biopsy.

RESULTS

Two different main types could be identified according to the presence or absence of ramifications. The apparently multifocal occurrence (in 2-D) of glandular epithelium was not confirmed by the 3-D study that showed that all epithelial glands are interconnected by luminal structures in each peritoneal lesion. Stereometric study suggests a stronger effect of gonadotropin-releasing hormone agonist therapy on the stroma than on the epithelium.

CONCLUSIONS

The study evaluated the 3-D architectures of peritoneal endometriosis and identified two principal types of peritoneal endometriosis.

摘要

目的

阐明腹膜子宫内膜异位症的一些生物学特性。

设计

应用一种最近发展起来的立体计算机技术来研究腹膜子宫内膜异位症的三维结构。

地点

大学妇科医院。

患者

从42例腹膜子宫内膜异位症女性患者身上获取活检样本。其中26例处于黄体期。17例在活检前接受了12周的诺雷德(英国剑桥 ICI 公司生产)治疗。

结果

根据有无分支可识别出两种不同的主要类型。二维研究中腺上皮明显多灶性出现的情况,三维研究未证实,三维研究表明每个腹膜病变中的所有上皮腺体通过腔隙结构相互连接。立体测量研究表明,促性腺激素释放激素激动剂治疗对间质的作用比对上皮的作用更强。

结论

该研究评估了腹膜子宫内膜异位症的三维结构,并确定了腹膜子宫内膜异位症的两种主要类型。

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