Witt Colleen, Raychaudhuri Subhadip, Chakraborty Arup K
University of California, Berkeley, CA 94720, USA.
J Exp Med. 2005 Feb 21;201(4):501-4. doi: 10.1084/jem.20050197.
Immunological phenomena that were once deduced from genetic, biochemical, and in situ approaches are now being witnessed in living color, in three dimensions, and in real time. The information in time-lapse imaging can provide valuable mechanistic insight into a host of processes, from cell migration to signal transduction. What we need now are methods to quantitate these new visual data and to exploit computational resources and statistical mechanical methods to develop mechanistic models.
曾经从遗传学、生物化学和原位方法推导出来的免疫现象，现在正以生动的色彩、三维形式和实时状态展现在我们眼前。延时成像中的信息可以为从细胞迁移到信号转导等一系列过程提供有价值的机制性见解。我们现在需要的是量化这些新视觉数据的方法，以及利用计算资源和统计力学方法来开发机制模型。
