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[通过家长教育降低轻度和中度铅中毒儿童血铅水平:一项随机对照研究]

[Parental education to reduce blood lead levels in children with mild and moderate lead poisoning: a randomized controlled study].

作者信息

Shen Xiao-ming, Yan Chong-huai, Wu Sheng-hu, Shi Rong

机构信息

Xinhua Hospital, Shanghai Children's Medical Center, Shanghai Institute for Pediatric Research, Research Center for Environmental Medicine of Children, Shanghai Second Medical University, 1665 Kong Jiang Road, Shanghai 200092, China.

出版信息

Zhonghua Er Ke Za Zhi. 2004 Dec;42(12):892-7.

Abstract

OBJECTIVE

To evaluate the effectiveness of parental education on reducing lead exposure of children by examining the changes in blood lead levels of children whose parents receiving or not receiving educational intervention.

METHODS

Two hundred children with confirmed blood lead levels beyond 100 microg/L were selected. They were randomized into two groups, 107 children in study group and 93 in control. At the beginning of the study, parents of both study and control groups were called for interview to complete KABP questionnaire and lead study questionnaire. The study group was provided with interventional measures while control group was not contacted until the end of study. Intervention of parental education was undertaken by means of a TV program, a set of slides and a brochure, and focused on the questions regarding harmful effects of lead poisoning, the sources of environmental lead and prevention of this preventable disease. Tests for blood lead level were repeated for both study and control groups 3 months after the determination of the initial blood lead level.

RESULTS

All the relevant knowledge of health effect, lead sources and prevention of childhood lead poisoning of participating parents of study group were improved significantly (chi(2) = 14.06, 13.07, 10.08, 28.26, P < 0.01) after educational intervention while parents control group also were significantly improved in the sub-catalogs of concept and prevention (chi(2) = 7.69, 8.64, P < 0.01), but not the health effect and sources of childhood lead poisoning. Children and parents' behavior in study group was improved accordingly and significantly. Less children ate popcorn (chi(2) = 4.08, P < 0.05), less children drank tap-water in the morning (chi(2) = 23.04, P < 0.01), more kids washed their hands before eating (chi(2) = 5.82, P < 0.05), less kids played on road side (chi(2) = 9.60, P < 0.01), and more parents changed their coat or took shower or washed hands before going home after work (chi(2) = 4.00, P < 0.05). But in the control group only the number of kids playing on road side was decreased significantly (chi(2) = 9.60, P < 0.01). A general decline in blood lead levels was detected in both groups with statistical significance at P < 0.01. However, the decrease in blood lead levels was more remarkable in the study group. There was average reduction of 55 microg/L (35%) in blood lead levels for study group (t = 4.979, P < 0.01) and an almost 33 microg/L (20%) for control (t = 3.398, P < 0.01). The reduction in blood lead level was 22 microg/L greater in study group (t = 3.531, P < 0.01). The study also showed that the effectiveness of the educational interventions depended upon various aspects. Fourteen variables were included in the stepwise multiple regression equation of blood lead level changes. Such as parents' occupational exposure to lead, the improvement of knowledge about prevention of childhood lead poisoning, the chang of habit of snacks intake, parents' education levels, the change of attitude of parents for the childhood lead poisoning, etc.

CONCLUSION

Educating parents is proved to be an effective approach for children with mild and moderate lead poisoning.

摘要

目的

通过检查接受或未接受教育干预的儿童父母的血铅水平变化,评估家长教育对降低儿童铅暴露的有效性。

方法

选取200名确诊血铅水平超过100μg/L的儿童。将他们随机分为两组,研究组107名儿童,对照组93名。在研究开始时,对研究组和对照组的父母进行访谈,以完成KABP问卷和铅研究问卷。研究组采取干预措施,而对照组在研究结束前不进行干预。通过电视节目、一组幻灯片和一本宣传册对家长进行教育干预,重点关注铅中毒的有害影响、环境铅源以及这种可预防疾病的预防等问题。在确定初始血铅水平3个月后,对研究组和对照组再次进行血铅水平检测。

结果

研究组参与家长关于儿童铅中毒的健康影响、铅源和预防的所有相关知识在教育干预后均有显著改善(χ² = 14.06、13.07、10.08、28.26,P < 0.01),而对照组家长在概念和预防子目录方面也有显著改善(χ² = 7.69、8.64,P < 0.01),但在儿童铅中毒的健康影响和铅源方面没有改善。研究组儿童及其父母的行为相应且显著改善。吃爆米花的儿童减少(χ² = 4.08,P < 0.05),早上喝自来水的儿童减少(χ² = 23.04,P < 0.01),饭前洗手的儿童增多(χ² = 5.82,P < 0.05),在路边玩耍的儿童减少(χ² = 9.60,P < 0.01),下班后回家前换衣服、洗澡或洗手的家长增多(χ² = 4.00,P < 0.05)。但对照组只有在路边玩耍的儿童数量显著减少(χ² = 9.60,P < 0.01)。两组血铅水平均普遍下降,差异有统计学意义(P < 0.01)。然而,研究组血铅水平下降更显著。研究组血铅水平平均降低55μg/L(35%)(t = 4.979,P < 0.01),对照组几乎降低33μg/L(20%)(t = 3.398,P < 0.01)。研究组血铅水平降低幅度比对照组大22μg/L(t = 3.531,P < 0.01)。研究还表明,教育干预的有效性取决于多个方面。血铅水平变化的逐步多元回归方程纳入了14个变量。如父母职业性铅暴露、儿童铅中毒预防知识的改善、零食摄入习惯的改变、父母教育水平、父母对儿童铅中毒态度的改变等。

结论

事实证明,对父母进行教育是治疗轻度和中度铅中毒儿童的有效方法。

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